Araştırma Makalesi
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Comparison of Nutritional Status with Serum Vitamin D and B12 Levels in Pregnant Women with Gestational Diabetes

Yıl 2023, Cilt: 9 Sayı: 2, 196 - 208, 31.05.2023
https://doi.org/10.19127/mbsjohs.1186891

Öz

Objective: In this study, it was aimed to evaluate the nutritional adequacy status of pregnant women with gestational diabetes and to examine the relationship between biochemical parameters such as vitamin D, vitamin B12, hemoglobin, hematocrit and fasting glucose.

Methods: In the study, serum vitamin D and B12 levels of 130 pregnant women between 24-28 weeks of gestation were examined. As a result of 75-gram oral glucose tolerance test, 70 pregnant women were diagnosed with gestational diabetes mellitus (GDM). The control group consisted of 60 healthy pregnant women. Nutritional factors were obtained through a questionnaire (anthropometric measurements, micronutrients, 3-day food consumption frequency, use of vitamin supplements) and groups were compared in terms of biochemical parameters (vitamin D, vitamin B12).

Results: Pregnant women with GDM; mean age (30.34 ± 5.28), family history of diabetes (17.1%), pre-pregnancy body mass index percentage (54.3%), rate of skipping meals were higher. The rate of use of vitamin and mineral supplements in pregnant women with GDM was low. According to the analysis of 3-day food consumption records of pregnant women with GDM, it was determined that the intake of micronutrients vitamin D and vitamin B12 was insufficient. Biochemical parameters such as vitamin D, vitamin B12, hemoglobin and hematocrit were found to be lower in pregnant women with GDM.

Conclusion: GDM is the most common endocrinological disorder in pregnancy. The study showed that inadequate nutrient intake negatively affects blood glucose levels and biochemical findings. Individuals with GDM should be referred to a nutritionist, medical nutrition therapy (TBT) appropriate for their individual characteristics should be given and monitored.

Destekleyen Kurum

Giresun University Scientific Research Projects

Proje Numarası

BAP-C-201218-99

Kaynakça

  • 1. Standards of medical care in diabetes 2013, American Diabetes Association. Diabetes care 2013; 36 Suppl 1(Suppl 1), s.11–66. https://doi.org/10.2337/dc13-S011/ (ET: 13.05.2018).
  • 2. Cho NH, Shaw JE, Karuranga S, Huang Y, da Rocha Fernandes JD, Ohlrogge AW, et al. IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes Res Clin Pract 2018; 138:271-281.
  • 3. Özyurt R, Asıcıoglu O, Gültekin T. Prevalence of Gestational Diabetes in Pregnant Women Admitted to the Gynecology and Obstetrics Clinic of Istanbul Training and Research Hospital. Journal of Gynecology, Obstetrics, Pediatrics and Pediatric Surgery 2013; 5(1):7-12. 16.
  • 4. Takiishi T, Gysemans C, Bouillon R, Mathieu C. Vitamin D and diabetes. Endocrinol Metab Clin North Am 2010; 39(2):419-46.
  • 5. Ley SH, Hanley AJ, Sermer M, Zinman B, O'Connor DL. Associations of prenatal metabolic abnormalities with insulin and adiponectin concentrations in human milk. Am J Clin Nutr 2012; 95(4):867-74.
  • 6. Standards of Medical Care in Diabetes 2012, American Diabetes Association. Diabetes Care 2012;35(Supplement1)http://care.diabetesjournals.org/content/35/Supplement_1/S11.abstract/ (ET: 13.05.2018).
  • 7. Parlea L, Bromberg IL, Feig DS, Vieth R, Merman E, Lipscombe LL. Association between serum 25-hydroxyvitamin D in early pregnancy and risk of gestational diabetes mellitus. Diabet Med 2012; 29(7): e25-32.
  • 8. Erkus E, Aktas G, Kocak MZ, Duman TT, Atak BM, Savli H. Diabetic regulation of subjects with type 2 diabetes mellitus is associated with serum vitamin D levels. Rev Assoc Med Bras 2019; 65(1):51-55.
  • 9. Ibrahim I, Bashir M, Singh P, Al Khodor S, Abdullahi H. The Impact of Nutritional Supplementation During Pregnancy on the Incidence of Gestational Diabetes and Glycaemia Control. Front Nutr. 2022 Apr 8;9:867099. doi: 10.3389/fnut.2022.867099.
  • 10. Trumbo P, Schlicker S, Yates AA, Poos M; Food and Nutrition Board of the Institute of Medicine, The National Academies. Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids. J Am Diet Assoc 2002; 102(11):1621-30.
  • 11. Konukoglu D. Vitamins. In: Aydın A, editor. Abstract Biochemistry for Tus. 4th Edition Istanbul: Turner Publishing; 2006. p.49-145.
  • 12. Bao W, Bowers K, Tobias DK, Hu FB, Zhang C. Prepregnancy dietary protein intake, major dietary protein sources, and the risk of gestational diabetes mellitus: a prospective cohort study. Diabetes Care 2013; 36(7):2001-8.
  • 13. Leng J, Shao P, Zhang C. Prevalence of gestational diabetes mellitus and its risk factors in Chinese pregnant women: a prospective population-based study in Tianjin, China. PLoS One 2015; 23;10(3): e0121029.
  • 14. Shin D, Song WO. Prepregnancy body mass index is an independent risk factor for gestational hypertension, gestational diabetes, preterm labor, and small- and large-for-gestational-age infants. J Matern Fetal Neonatal Med 2015; 28(14):1679-86.
  • 15. Schummers L, Hutcheon JA, Bodnar LM, Lieberman E, Himes KP. Risk of Adverse Pregnancy Outcomes by Prepregnancy Body Mass Index: A Population-Based Study to Inform Prepregnancy Weight Loss Counseling. Obstetrics & Gynecology 2015; 125 (1), 133-143.
  • 16. Gul K. 2016. Are snacks necessary for diabetic patients? Turkish Diabetes Yearbook. http://www.diabetcemiyeti.org/diyabetli_hastalara_ara_ogun_gerekli_mi? / (ET: 17.06.2018).
  • 17. Diagnosis and classification of diabetes mellitus 2014, American Diabetes Association. Diabetes care 2014; 37 Suppl 1, s81–90. https://doi.org/10.2337/dc14-S081/ (ET: 17.06.2018).
  • 18. Zhang C, Liu S, Solomon CG. Dietary Fiber İntake, Dietary Glycemic Load, And The Risk For Gestational Diabetes Mellitus. Diabetes Care 2006; 29(10):2223-30.
  • 19. Lee P. PTH-vitamin D-glycemia interactions reloaded. Diabetes 2014; 63(11):3593-5.
  • 20. Lu M, Xu Y, Lv L, Zhang M. Association between vitamin D status and the risk of gestational diabetes mellitus: a meta-analysis. Archives of Gynecology and Obstetrics. 2016;293(5):959–966. doi: 10.1007/s00404-016-4010-4.
  • 21. Burris HH, Rifas-Shiman SL, Kleinman K, Litonjua AA, Huh SY, Rich-Edwards JW, et al. Vitamin D deficiency in pregnancy and gestational diabetes mellitus. American Journal of Obstetrics And Gynecology 2012; 207 (3), 182 – 188.
  • 22. Gurz AA. Fetal and Maternal Effects of Vitamin D, Konuralp Medical Journal 2015; 7(1):69-75.
  • 23. Krishnaveni GV, Hill JC, Veena SR, Bhat DS, Wills AK, Karat CL, et al. Low plasma vitamin B12 in pregnancy is associated with gestational 'diabesity' and later diabetes. Diabetologia 2009; 52(11):2350-8.
Yıl 2023, Cilt: 9 Sayı: 2, 196 - 208, 31.05.2023
https://doi.org/10.19127/mbsjohs.1186891

Öz

Proje Numarası

BAP-C-201218-99

Kaynakça

  • 1. Standards of medical care in diabetes 2013, American Diabetes Association. Diabetes care 2013; 36 Suppl 1(Suppl 1), s.11–66. https://doi.org/10.2337/dc13-S011/ (ET: 13.05.2018).
  • 2. Cho NH, Shaw JE, Karuranga S, Huang Y, da Rocha Fernandes JD, Ohlrogge AW, et al. IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes Res Clin Pract 2018; 138:271-281.
  • 3. Özyurt R, Asıcıoglu O, Gültekin T. Prevalence of Gestational Diabetes in Pregnant Women Admitted to the Gynecology and Obstetrics Clinic of Istanbul Training and Research Hospital. Journal of Gynecology, Obstetrics, Pediatrics and Pediatric Surgery 2013; 5(1):7-12. 16.
  • 4. Takiishi T, Gysemans C, Bouillon R, Mathieu C. Vitamin D and diabetes. Endocrinol Metab Clin North Am 2010; 39(2):419-46.
  • 5. Ley SH, Hanley AJ, Sermer M, Zinman B, O'Connor DL. Associations of prenatal metabolic abnormalities with insulin and adiponectin concentrations in human milk. Am J Clin Nutr 2012; 95(4):867-74.
  • 6. Standards of Medical Care in Diabetes 2012, American Diabetes Association. Diabetes Care 2012;35(Supplement1)http://care.diabetesjournals.org/content/35/Supplement_1/S11.abstract/ (ET: 13.05.2018).
  • 7. Parlea L, Bromberg IL, Feig DS, Vieth R, Merman E, Lipscombe LL. Association between serum 25-hydroxyvitamin D in early pregnancy and risk of gestational diabetes mellitus. Diabet Med 2012; 29(7): e25-32.
  • 8. Erkus E, Aktas G, Kocak MZ, Duman TT, Atak BM, Savli H. Diabetic regulation of subjects with type 2 diabetes mellitus is associated with serum vitamin D levels. Rev Assoc Med Bras 2019; 65(1):51-55.
  • 9. Ibrahim I, Bashir M, Singh P, Al Khodor S, Abdullahi H. The Impact of Nutritional Supplementation During Pregnancy on the Incidence of Gestational Diabetes and Glycaemia Control. Front Nutr. 2022 Apr 8;9:867099. doi: 10.3389/fnut.2022.867099.
  • 10. Trumbo P, Schlicker S, Yates AA, Poos M; Food and Nutrition Board of the Institute of Medicine, The National Academies. Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids. J Am Diet Assoc 2002; 102(11):1621-30.
  • 11. Konukoglu D. Vitamins. In: Aydın A, editor. Abstract Biochemistry for Tus. 4th Edition Istanbul: Turner Publishing; 2006. p.49-145.
  • 12. Bao W, Bowers K, Tobias DK, Hu FB, Zhang C. Prepregnancy dietary protein intake, major dietary protein sources, and the risk of gestational diabetes mellitus: a prospective cohort study. Diabetes Care 2013; 36(7):2001-8.
  • 13. Leng J, Shao P, Zhang C. Prevalence of gestational diabetes mellitus and its risk factors in Chinese pregnant women: a prospective population-based study in Tianjin, China. PLoS One 2015; 23;10(3): e0121029.
  • 14. Shin D, Song WO. Prepregnancy body mass index is an independent risk factor for gestational hypertension, gestational diabetes, preterm labor, and small- and large-for-gestational-age infants. J Matern Fetal Neonatal Med 2015; 28(14):1679-86.
  • 15. Schummers L, Hutcheon JA, Bodnar LM, Lieberman E, Himes KP. Risk of Adverse Pregnancy Outcomes by Prepregnancy Body Mass Index: A Population-Based Study to Inform Prepregnancy Weight Loss Counseling. Obstetrics & Gynecology 2015; 125 (1), 133-143.
  • 16. Gul K. 2016. Are snacks necessary for diabetic patients? Turkish Diabetes Yearbook. http://www.diabetcemiyeti.org/diyabetli_hastalara_ara_ogun_gerekli_mi? / (ET: 17.06.2018).
  • 17. Diagnosis and classification of diabetes mellitus 2014, American Diabetes Association. Diabetes care 2014; 37 Suppl 1, s81–90. https://doi.org/10.2337/dc14-S081/ (ET: 17.06.2018).
  • 18. Zhang C, Liu S, Solomon CG. Dietary Fiber İntake, Dietary Glycemic Load, And The Risk For Gestational Diabetes Mellitus. Diabetes Care 2006; 29(10):2223-30.
  • 19. Lee P. PTH-vitamin D-glycemia interactions reloaded. Diabetes 2014; 63(11):3593-5.
  • 20. Lu M, Xu Y, Lv L, Zhang M. Association between vitamin D status and the risk of gestational diabetes mellitus: a meta-analysis. Archives of Gynecology and Obstetrics. 2016;293(5):959–966. doi: 10.1007/s00404-016-4010-4.
  • 21. Burris HH, Rifas-Shiman SL, Kleinman K, Litonjua AA, Huh SY, Rich-Edwards JW, et al. Vitamin D deficiency in pregnancy and gestational diabetes mellitus. American Journal of Obstetrics And Gynecology 2012; 207 (3), 182 – 188.
  • 22. Gurz AA. Fetal and Maternal Effects of Vitamin D, Konuralp Medical Journal 2015; 7(1):69-75.
  • 23. Krishnaveni GV, Hill JC, Veena SR, Bhat DS, Wills AK, Karat CL, et al. Low plasma vitamin B12 in pregnancy is associated with gestational 'diabesity' and later diabetes. Diabetologia 2009; 52(11):2350-8.
Toplam 23 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Araştırma Makaleleri
Yazarlar

Tevhide Çelenk 0000-0002-9364-0802

Aysegul Cebi 0000-0003-3804-7966

Proje Numarası BAP-C-201218-99
Yayımlanma Tarihi 31 Mayıs 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 9 Sayı: 2

Kaynak Göster

Vancouver Çelenk T, Cebi A. Comparison of Nutritional Status with Serum Vitamin D and B12 Levels in Pregnant Women with Gestational Diabetes. Middle Black Sea Journal of Health Science. 2023;9(2):196-208.

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