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MORINGA OLEIFERA’NIN ETKİNLİK VE GÜVENLİĞİ

Yıl 2022, Cilt: 46 Sayı: 2, 487 - 504, 29.05.2022

Burçin Mersin Gülçin Saltan İşcan

https://doi.org/10.33483/jfpau.1021227
Cited By: 1

Öz

Amaç: Moringa oleifera Lamarck, Orta Doğu, Afrika ve Asya Ülkeleri’nde yetişen bir bitki olup; bu ülkelerde özellikle bitkinin tohumları ve yaprakları gıda olarak tüketilmektedir.
Sonuç ve Tartışma: Bitkinin yaprak ve tohum kısımları fitokimyasallar açısından oldukça zengin olup; flavonoit, glukosinolat, alkaloit, fenolik asit, terpen, sterol, mineral, vitamin, amino asitler ve yağ asitleri taşımaktadır. Tohumlardan elde edilen yağ ise; esansiyel yağ asitleri omega 3, 6 ve 9 açısından çok zengin olması sebebiyle zeytinyağına alternatif bir besin kaynağı olarak görülmektedir. Bitkinin tüm kısımları (yaprak, tohum, kök ve çiçek) insan ve hayvan tüketimine uygun olarak bulunmuştur. Bununla birlikte bitkinin su arıtımı, biyodizel olarak kullanımı, kozmetik sektörü gibi gıda dışı alanlarda da değerlendirildiği bilinmektedir. Bitkinin biyolojik etkileri konusunda uluslararası saygın dergilerde yayımlanmış bilimsel çalışmalar mevcuttur. Yapılan araştırmalar ile bitkinin içerdiği fitokimyasallar sebebiyle antioksidan, antimikrobiyal, antikanser, antidiyabetik ve kardiyovasküler riskleri önleyici etkileri ispatlanmıştır.

Anahtar Kelimeler

Biyolojik aktivite Moringa oleifera Moringa yağı protein yağ asitleri

Kaynakça

  • 1. Ghazali, Hasanah Mohd, & Mohammed, Abdulkarim Sabo. (2011). Moringa (Moringa oleifera) Seed Oil. In Nuts and Seeds in Health and Disease Prevention (pp. 787-793).
  • 2. Abd Rani, N. Z., Husain, K., & Kumolosasi, E. (2018). Moringa Genus: A Review of Phytochemistry and Pharmacology. Front Pharmacol, 9, 108. [CrossRef]
  • 3. The Plant List Web site. (2021), http://www.theplantlist.org/tpl1.1/search?q=moringa, Erişim tarihi: 21 Mart 2021.
  • 4. Saa, Romuald Willy, Fombang, Edith Nig, Ndjantou, Elie Baudelaire, & Njintang, Nicolas Yanou. (2019). Treatments and uses of Moringa oleifera seeds in human nutrition: A review. Food science & nutrition, 7(6), 1911-1919.
  • 5. Mahfuz, S., & Piao, X. S. (2019). Application of Moringa (Moringa oleifera) as Natural Feed Supplement in Poultry Diets. Animals (Basel), 9(7). [CrossRef]
  • 6. Parrotta, J. A. (1993). Moringa Oleifera Lam: Resedá, Horseradish Tree, Moringaceae, Horseradish-tree Family. International Institute of Tropical Forestry. US Department of Agriculture, Forest Service.
  • 7. Leone, A., Spada, A., Battezzati, A., Schiraldi, A., Aristil, J., & Bertoli, S. (2015). Cultivation, Genetic, Ethnopharmacology, Phytochemistry and Pharmacology of Moringa oleifera Leaves: An Overview. Int J Mol Sci, 16(6), 12791-12835. [CrossRef]
  • 8. Richter, Nahid, Siddhuraju, Perumal, & Becker, Klaus. (2003). Evaluation of nutritional quality of moringa (Moringa oleifera Lam.) leaves as an alternative protein source for Nile tilapia (Oreochromis niloticus L.). Aquaculture, 217(1-4), 599-611. [CrossRef]
  • 9. Leone, A., Spada, A., Battezzati, A., Schiraldi, A., Aristil, J., & Bertoli, S. (2016). Moringa oleifera Seeds and Oil: Characteristics and Uses for Human Health. Int J Mol Sci, 17(12). [CrossRef]
  • 10. Kayode, R. M., & Afolayan, A. J. (2015). Cytotoxicity and effect of extraction methods on the chemical composition of essential oils of Moringa oleifera seeds. J Zhejiang Univ Sci B, 16(8), 680-689. [CrossRef]
  • 11. Gharsallah, Karima, Rezig, Leila, Msaada, Kamel, Chalh, Abdellah, & Soltani, Taoufik. (2021). Chemical composition and profile characterization of moringa oleifera seed oil. South African Journal of Botany, 137, 475-482. [CrossRef]
  • 12. Zhao, Beibei, Li, Hua, Lan, Tao, Wu, Di, & Chen, Zhicheng. (2019). Characterization of the Chemical Composition of Chinese Moringa oleifera Seed Oil. Journal of the American Oil Chemists' Society, 96(5), 523-533. [CrossRef]
  • 13. Mbah, B. O., Eme, P. E., & Ogbusu, O. F. (2012). Effect of cooking methods (boiling and roasting) on nutrients and anti-nutrients content of Moringa oleifera seeds. Pakistan Journal of Nutrition, 11(3), 211. [CrossRef]
  • 14. Tsaknis, J., Lalas, S., Gergis, V., Dourtoglou, V., & Spiliotis, V. (1999). Characterization of Moringa oleifera variety Mbololo seed oil of Kenya. Journal of Agricultural and food chemistry, 47(11), 4495-4499. [CrossRef]
  • 15. Brunelli, D., Tavecchio, M., Falcioni, C., Frapolli, R., Erba, E., Iori, R., . . . D'Incalci, M. (2010). The isothiocyanate produced from glucomoringin inhibits NF-kB and reduces myeloma growth in nude mice in vivo. Biochem Pharmacol, 79(8), 1141-1148. [CrossRef]
  • 16. Singh, R. G., Negi, P. S., & Radha, C. (2013). Phenolic composition, antioxidant and antimicrobial activities of free and bound phenolic extracts of Moringa oleifera seed flour. Journal of functional foods, 5(4), 1883-1891.
  • 17. Teixeira, E. M., Carvalho, M. R., Neves, V. A., Silva, M. A., & Arantes-Pereira, L. (2014). Chemical characteristics and fractionation of proteins from Moringa oleifera Lam. leaves. Food Chem, 147, 51-54. [CrossRef]
  • 18. Özcan, M. M., Ghafoor, K., Al Juhaimi, F., Ahmed, I. A. M., & Babiker, E. E. (2019). Effect of cold-press and soxhlet extraction on fatty acids, tocopherols and sterol contents of the Moringa seed oils. South African Journal of Botany, 124, 333-337. [CrossRef]
  • 19. Koike, M. K., Kochi, A. K., & Pinto, D. Y. G. (2020). Use of Moringa Oleifera Seeds in Water Treatment. Arq Bras Cardiol, 114(6), 1038-1039. [CrossRef]
  • 20. Gopalakrishnan, Lakshmipriya, Doriya, Kruthi, & Kumar, Devarai Santhosh. (2016). Moringa oleifera: A review on nutritive importance and its medicinal application. Food Science and Human Wellness, 5(2), 49-56. [CrossRef]
  • 21. Kou, X., Li, B., Olayanju, J. B., Drake, J. M., & Chen, N. (2018). Nutraceutical or Pharmacological Potential of Moringa oleifera Lam. Nutrients, 10(3). [CrossRef] 22. Dhakad, A. K., Ikram, M., Sharma, S., Khan, S., Pandey, V. V., & Singh, A. (2019). Biological, nutritional, and therapeutic significance of Moringa oleifera Lam. Phytother Res, 33(11), 2870-2903. [CrossRef]
  • 23. Jacques, A. S., Arnaud, S. S., Fr&ejus, O. O., & Jacques, D. T. . (2020). Review on biological and immunomodulatory properties of Moringa oleifera in animal and human nutrition. . Journal of Pharmacognosy and Phytotherapy, 12(1), 1-9. [CrossRef]
  • 24. Li, Y. J., Ji, Q. Q., Wang, Z., Shen, L. H., & He, B. (2020). Moringa oleifera seeds mitigate myocardial injury and prevent ventricular failure induced by myocardial infarction. Am J Transl Res, 12(8), 4511-4521.
  • 25. Fatoumata, B. A., MamadouSaïdou, B. A. H., Mohamet, Sene, Joseph, Koulanzo Sambou, Modou, Mbacké Gueye, & El, HadjiMakhtar B. A. (2020). Antidiabetic properties of Moringa oleifera: A review of the literature. Journal of Diabetes and Endocrinology, 11(1), 18-29. [CrossRef]
  • 26. Gupta, R., Mathur, M., Bajaj, V. K., Katariya, P., Yadav, S., Kamal, R., & Gupta, R. S. (2012). Evaluation of antidiabetic and antioxidant activity of Moringa oleifera in experimental diabetes. J Diabetes, 4(2), 164-171. [CrossRef]
  • 27. Ma, Z. F., Ahmad, J., Zhang, H., Khan, I., & Muhammad, S. (2020). Evaluation of phytochemical and medicinal properties of Moringa (Moringa oleifera) as a potential functional food. South African Journal of Botany, 129, 40-46. [CrossRef]
  • 28. Villarruel-Lopez, A., Lopez-de la Mora, D. A., Vazquez-Paulino, O. D., Puebla-Mora, A. G., Torres-Vitela, M. R., Guerrero-Quiroz, L. A., & Nuno, K. (2018). Effect of Moringa oleifera consumption on diabetic rats. BMC Complement Altern Med, 18(1), 127. [CrossRef]
  • 29. Vargas-Sanchez, K., Garay-Jaramillo, E., & Gonzalez-Reyes, R. E. (2019). Effects of Moringa oleifera on Glycaemia and Insulin Levels: A Review of Animal and Human Studies. Nutrients, 11(12). [CrossRef]
  • 30. Haber, S. L., McMahon, R. P., Barajas, J., Hayes, A. R., & Hussein, H. (2020). Effects of Moringa oleifera in patients with type 2 diabetes. Am J Health Syst Pharm, 77(22), 1834-1837. [CrossRef]
  • 31. Suphachai, Charoensin. (2014). Antioxidant and anticancer activities of Moringa oleifera leaves. Journal of Medicinal Plants Research, 8(7), 318-325. [CrossRef]
  • 32. Islam, Z., Islam, S. M. R., Hossen, F., Mahtab-Ul-Islam, K., Hasan, M. R., & Karim, R. (2021). Moringa oleifera is a Prominent Source of Nutrients with Potential Health Benefits. Int J Food Sci, 2021, 6627265. [CrossRef]
  • 33. Wisitpongpun, P., Suphrom, N., Potup, P., Nuengchamnong, N., Calder, P. C., & Usuwanthim, K. (2020). In Vitro Bioassay-Guided Identification of Anticancer Properties from Moringa oleifera Lam. Leaf against the MDA-MB-231 Cell Line. Pharmaceuticals (Basel), 13(12). [CrossRef]
  • 34. Karim, N. A. A., Ibrahim, M. D., Kntayya, S. B., Rukayadi, Y., Hamid, H. A., & Razis, A. F. A. (2016). Moringa oleifera Lam targeting chemoprevention. Asian Pacific Journal of Cancer Prevention, 17(8), 3675-3686.
  • 35. Varalakshmi, K. N., & Nair, Shruti. (2011). Anticancer, cytotoxic potential of Moringa oleifera extracts on HeLa cell line. Journal of Natural Pharmaceuticals, 2(3). [CrossRef] 36. Al-Asmari, A. K., Albalawi, S. M., Athar, M. T., Khan, A. Q., Al-Shahrani, H., & Islam, M. (2015). Moringa oleifera as an anti-cancer agent against breast and colorectal cancer cell lines. PloS one, 10(8), e0135814. [CrossRef]
  • 37. Szlachetka, Kinga, Kut, Paulina, & Stępień, Agnieszka. (2020). Cytotoxic and anticancer activity of Moringa oleifera. European Journal of Clinical and Experimental Medicine, 18(3), 214-220. [CrossRef]
  • 38. Saleem, Ammara, Saleem, Mohammad, & Akhtar, Muhammad Furqan. (2020). Antioxidant, anti-inflammatory and antiarthritic potential of Moringa oleifera Lam: An ethnomedicinal plant of Moringaceae family. South African Journal of Botany, 128, 246-256. [CrossRef]
  • 39. Mansour, M., Sherif, M., Ismail, Y., Abd Elhameed, A., & Awad, S. (2021). Study of The Possible Effect of Fluoxetine, Moringa Oleifera and Methotrexate in A Rat Model Of Rheumatoid Arthritis. Benha Medical Journal. [CrossRef]
  • 40. V. Balamurugan*, L . Muruganandam. (2021). IN-VITRO ANTI-INFLAMMATORY AND ANTI-ARTHRITIC ACTIVITY OF CARDIOSPERMUM HALICACABUM AND MORINGA OLEIFERA LEAVES EXTRACT. Journal of Advanced Scientific Research.
  • 41. Kumar, V., Verma, A., Ahmed, D., Sachan, N. K., Anwar, F., & Mujeeb, M. (2013). Fostered antiarthritic upshot of moringa oleifera lam. stem bark extract in diversely induced arthritis in wistar rats with plausible mechanism. International journal of pharmaceutical sciences and research, 4(10), 3894-01. [CrossRef]
  • 42. Wang, F., Bao, Y., Zhang, C., Zhan, L., Khan, W., Siddiqua, S., . . . Xiao, J. (2021). Bioactive components and anti-diabetic properties of Moringa oleifera Lam. Crit Rev Food Sci Nutr, 1-25.
  • 43. Anwar, F., & Rashid, U. (2007). Physico-chemical characteristics of Moringa oleifera seeds and seed oil from a wild provenance of Pakistan. Pak. J. Bot, 39(5), 1443-1453.
  • 44. Oyeyinka, Adewumi T., & Oyeyinka, Samson A. (2018). Moringa oleifera as a food fortificant: Recent trends and prospects. Journal of the Saudi Society of Agricultural Sciences, 17(2), 127-136. [CrossRef]
  • 45. Lin, Mengfei, Zhang, Junjie, & Chen, Xiaoyang. (2018). Bioactive flavonoids in Moringa oleifera and their health-promoting properties. Journal of Functional Foods, 47, 469-479. [CrossRef]
  • 46. Kumar, G., Giri, A., Arya, R., Tyagi, R., Mishra, S., Mishra, A. K., & Datta, J. . (2019). Multifaceted applications of different parts of Moringa species: Review of present status and future potentials. International Journal of Chemical Studies, 7(2), 835-842.

SAFETY AND EFFICACY OF MORINGA OLEIFERA

Yıl 2022, Cilt: 46 Sayı: 2, 487 - 504, 29.05.2022

Burçin Mersin Gülçin Saltan İşcan

https://doi.org/10.33483/jfpau.1021227
Cited By: 1

Öz

Objective: Moringa oleifera Lamarck is a plant grown in Middle East, Africa and Asian countries, where seeds and leaves of the plant are consumed as food in these countries.
Result and Discussion: The leaf and seed parts of the plant are very rich in phytochemicals; high content of flavonoids, glucosinolates, alkaloids, phenolic acids, terpenes, sterols, vitamins, minerals, amino acids and fatty acids. As for the oil obtained from the seeds; It is seen as an alternative food source to olive oil because it is very rich in essential fatty acids omega 3, 6 and 9. All parts of the plant (leaves, seeds, roots and flowers) were found suitable for human and animal consumption. However, it is known that the plant is also used in non-food areas such as water treatment, use as biodiesel, and cosmetics sector. There are scientific studies published in internationally respected journals about the biological effects of plant. The researches revealed that, phytochemicals contained in the plant have proven their antioxidant, antimicrobial, anticancer, antidiabetic and preventive effects on cardiovascular risks.

Anahtar Kelimeler

Biological activity Moringa oleifera Moringa oil protein fatty acids

Kaynakça

  • 1. Ghazali, Hasanah Mohd, & Mohammed, Abdulkarim Sabo. (2011). Moringa (Moringa oleifera) Seed Oil. In Nuts and Seeds in Health and Disease Prevention (pp. 787-793).
  • 2. Abd Rani, N. Z., Husain, K., & Kumolosasi, E. (2018). Moringa Genus: A Review of Phytochemistry and Pharmacology. Front Pharmacol, 9, 108. [CrossRef]
  • 3. The Plant List Web site. (2021), http://www.theplantlist.org/tpl1.1/search?q=moringa, Erişim tarihi: 21 Mart 2021.
  • 4. Saa, Romuald Willy, Fombang, Edith Nig, Ndjantou, Elie Baudelaire, & Njintang, Nicolas Yanou. (2019). Treatments and uses of Moringa oleifera seeds in human nutrition: A review. Food science & nutrition, 7(6), 1911-1919.
  • 5. Mahfuz, S., & Piao, X. S. (2019). Application of Moringa (Moringa oleifera) as Natural Feed Supplement in Poultry Diets. Animals (Basel), 9(7). [CrossRef]
  • 6. Parrotta, J. A. (1993). Moringa Oleifera Lam: Resedá, Horseradish Tree, Moringaceae, Horseradish-tree Family. International Institute of Tropical Forestry. US Department of Agriculture, Forest Service.
  • 7. Leone, A., Spada, A., Battezzati, A., Schiraldi, A., Aristil, J., & Bertoli, S. (2015). Cultivation, Genetic, Ethnopharmacology, Phytochemistry and Pharmacology of Moringa oleifera Leaves: An Overview. Int J Mol Sci, 16(6), 12791-12835. [CrossRef]
  • 8. Richter, Nahid, Siddhuraju, Perumal, & Becker, Klaus. (2003). Evaluation of nutritional quality of moringa (Moringa oleifera Lam.) leaves as an alternative protein source for Nile tilapia (Oreochromis niloticus L.). Aquaculture, 217(1-4), 599-611. [CrossRef]
  • 9. Leone, A., Spada, A., Battezzati, A., Schiraldi, A., Aristil, J., & Bertoli, S. (2016). Moringa oleifera Seeds and Oil: Characteristics and Uses for Human Health. Int J Mol Sci, 17(12). [CrossRef]
  • 10. Kayode, R. M., & Afolayan, A. J. (2015). Cytotoxicity and effect of extraction methods on the chemical composition of essential oils of Moringa oleifera seeds. J Zhejiang Univ Sci B, 16(8), 680-689. [CrossRef]
  • 11. Gharsallah, Karima, Rezig, Leila, Msaada, Kamel, Chalh, Abdellah, & Soltani, Taoufik. (2021). Chemical composition and profile characterization of moringa oleifera seed oil. South African Journal of Botany, 137, 475-482. [CrossRef]
  • 12. Zhao, Beibei, Li, Hua, Lan, Tao, Wu, Di, & Chen, Zhicheng. (2019). Characterization of the Chemical Composition of Chinese Moringa oleifera Seed Oil. Journal of the American Oil Chemists' Society, 96(5), 523-533. [CrossRef]
  • 13. Mbah, B. O., Eme, P. E., & Ogbusu, O. F. (2012). Effect of cooking methods (boiling and roasting) on nutrients and anti-nutrients content of Moringa oleifera seeds. Pakistan Journal of Nutrition, 11(3), 211. [CrossRef]
  • 14. Tsaknis, J., Lalas, S., Gergis, V., Dourtoglou, V., & Spiliotis, V. (1999). Characterization of Moringa oleifera variety Mbololo seed oil of Kenya. Journal of Agricultural and food chemistry, 47(11), 4495-4499. [CrossRef]
  • 15. Brunelli, D., Tavecchio, M., Falcioni, C., Frapolli, R., Erba, E., Iori, R., . . . D'Incalci, M. (2010). The isothiocyanate produced from glucomoringin inhibits NF-kB and reduces myeloma growth in nude mice in vivo. Biochem Pharmacol, 79(8), 1141-1148. [CrossRef]
  • 16. Singh, R. G., Negi, P. S., & Radha, C. (2013). Phenolic composition, antioxidant and antimicrobial activities of free and bound phenolic extracts of Moringa oleifera seed flour. Journal of functional foods, 5(4), 1883-1891.
  • 17. Teixeira, E. M., Carvalho, M. R., Neves, V. A., Silva, M. A., & Arantes-Pereira, L. (2014). Chemical characteristics and fractionation of proteins from Moringa oleifera Lam. leaves. Food Chem, 147, 51-54. [CrossRef]
  • 18. Özcan, M. M., Ghafoor, K., Al Juhaimi, F., Ahmed, I. A. M., & Babiker, E. E. (2019). Effect of cold-press and soxhlet extraction on fatty acids, tocopherols and sterol contents of the Moringa seed oils. South African Journal of Botany, 124, 333-337. [CrossRef]
  • 19. Koike, M. K., Kochi, A. K., & Pinto, D. Y. G. (2020). Use of Moringa Oleifera Seeds in Water Treatment. Arq Bras Cardiol, 114(6), 1038-1039. [CrossRef]
  • 20. Gopalakrishnan, Lakshmipriya, Doriya, Kruthi, & Kumar, Devarai Santhosh. (2016). Moringa oleifera: A review on nutritive importance and its medicinal application. Food Science and Human Wellness, 5(2), 49-56. [CrossRef]
  • 21. Kou, X., Li, B., Olayanju, J. B., Drake, J. M., & Chen, N. (2018). Nutraceutical or Pharmacological Potential of Moringa oleifera Lam. Nutrients, 10(3). [CrossRef] 22. Dhakad, A. K., Ikram, M., Sharma, S., Khan, S., Pandey, V. V., & Singh, A. (2019). Biological, nutritional, and therapeutic significance of Moringa oleifera Lam. Phytother Res, 33(11), 2870-2903. [CrossRef]
  • 23. Jacques, A. S., Arnaud, S. S., Fr&ejus, O. O., & Jacques, D. T. . (2020). Review on biological and immunomodulatory properties of Moringa oleifera in animal and human nutrition. . Journal of Pharmacognosy and Phytotherapy, 12(1), 1-9. [CrossRef]
  • 24. Li, Y. J., Ji, Q. Q., Wang, Z., Shen, L. H., & He, B. (2020). Moringa oleifera seeds mitigate myocardial injury and prevent ventricular failure induced by myocardial infarction. Am J Transl Res, 12(8), 4511-4521.
  • 25. Fatoumata, B. A., MamadouSaïdou, B. A. H., Mohamet, Sene, Joseph, Koulanzo Sambou, Modou, Mbacké Gueye, & El, HadjiMakhtar B. A. (2020). Antidiabetic properties of Moringa oleifera: A review of the literature. Journal of Diabetes and Endocrinology, 11(1), 18-29. [CrossRef]
  • 26. Gupta, R., Mathur, M., Bajaj, V. K., Katariya, P., Yadav, S., Kamal, R., & Gupta, R. S. (2012). Evaluation of antidiabetic and antioxidant activity of Moringa oleifera in experimental diabetes. J Diabetes, 4(2), 164-171. [CrossRef]
  • 27. Ma, Z. F., Ahmad, J., Zhang, H., Khan, I., & Muhammad, S. (2020). Evaluation of phytochemical and medicinal properties of Moringa (Moringa oleifera) as a potential functional food. South African Journal of Botany, 129, 40-46. [CrossRef]
  • 28. Villarruel-Lopez, A., Lopez-de la Mora, D. A., Vazquez-Paulino, O. D., Puebla-Mora, A. G., Torres-Vitela, M. R., Guerrero-Quiroz, L. A., & Nuno, K. (2018). Effect of Moringa oleifera consumption on diabetic rats. BMC Complement Altern Med, 18(1), 127. [CrossRef]
  • 29. Vargas-Sanchez, K., Garay-Jaramillo, E., & Gonzalez-Reyes, R. E. (2019). Effects of Moringa oleifera on Glycaemia and Insulin Levels: A Review of Animal and Human Studies. Nutrients, 11(12). [CrossRef]
  • 30. Haber, S. L., McMahon, R. P., Barajas, J., Hayes, A. R., & Hussein, H. (2020). Effects of Moringa oleifera in patients with type 2 diabetes. Am J Health Syst Pharm, 77(22), 1834-1837. [CrossRef]
  • 31. Suphachai, Charoensin. (2014). Antioxidant and anticancer activities of Moringa oleifera leaves. Journal of Medicinal Plants Research, 8(7), 318-325. [CrossRef]
  • 32. Islam, Z., Islam, S. M. R., Hossen, F., Mahtab-Ul-Islam, K., Hasan, M. R., & Karim, R. (2021). Moringa oleifera is a Prominent Source of Nutrients with Potential Health Benefits. Int J Food Sci, 2021, 6627265. [CrossRef]
  • 33. Wisitpongpun, P., Suphrom, N., Potup, P., Nuengchamnong, N., Calder, P. C., & Usuwanthim, K. (2020). In Vitro Bioassay-Guided Identification of Anticancer Properties from Moringa oleifera Lam. Leaf against the MDA-MB-231 Cell Line. Pharmaceuticals (Basel), 13(12). [CrossRef]
  • 34. Karim, N. A. A., Ibrahim, M. D., Kntayya, S. B., Rukayadi, Y., Hamid, H. A., & Razis, A. F. A. (2016). Moringa oleifera Lam targeting chemoprevention. Asian Pacific Journal of Cancer Prevention, 17(8), 3675-3686.
  • 35. Varalakshmi, K. N., & Nair, Shruti. (2011). Anticancer, cytotoxic potential of Moringa oleifera extracts on HeLa cell line. Journal of Natural Pharmaceuticals, 2(3). [CrossRef] 36. Al-Asmari, A. K., Albalawi, S. M., Athar, M. T., Khan, A. Q., Al-Shahrani, H., & Islam, M. (2015). Moringa oleifera as an anti-cancer agent against breast and colorectal cancer cell lines. PloS one, 10(8), e0135814. [CrossRef]
  • 37. Szlachetka, Kinga, Kut, Paulina, & Stępień, Agnieszka. (2020). Cytotoxic and anticancer activity of Moringa oleifera. European Journal of Clinical and Experimental Medicine, 18(3), 214-220. [CrossRef]
  • 38. Saleem, Ammara, Saleem, Mohammad, & Akhtar, Muhammad Furqan. (2020). Antioxidant, anti-inflammatory and antiarthritic potential of Moringa oleifera Lam: An ethnomedicinal plant of Moringaceae family. South African Journal of Botany, 128, 246-256. [CrossRef]
  • 39. Mansour, M., Sherif, M., Ismail, Y., Abd Elhameed, A., & Awad, S. (2021). Study of The Possible Effect of Fluoxetine, Moringa Oleifera and Methotrexate in A Rat Model Of Rheumatoid Arthritis. Benha Medical Journal. [CrossRef]
  • 40. V. Balamurugan*, L . Muruganandam. (2021). IN-VITRO ANTI-INFLAMMATORY AND ANTI-ARTHRITIC ACTIVITY OF CARDIOSPERMUM HALICACABUM AND MORINGA OLEIFERA LEAVES EXTRACT. Journal of Advanced Scientific Research.
  • 41. Kumar, V., Verma, A., Ahmed, D., Sachan, N. K., Anwar, F., & Mujeeb, M. (2013). Fostered antiarthritic upshot of moringa oleifera lam. stem bark extract in diversely induced arthritis in wistar rats with plausible mechanism. International journal of pharmaceutical sciences and research, 4(10), 3894-01. [CrossRef]
  • 42. Wang, F., Bao, Y., Zhang, C., Zhan, L., Khan, W., Siddiqua, S., . . . Xiao, J. (2021). Bioactive components and anti-diabetic properties of Moringa oleifera Lam. Crit Rev Food Sci Nutr, 1-25.
  • 43. Anwar, F., & Rashid, U. (2007). Physico-chemical characteristics of Moringa oleifera seeds and seed oil from a wild provenance of Pakistan. Pak. J. Bot, 39(5), 1443-1453.
  • 44. Oyeyinka, Adewumi T., & Oyeyinka, Samson A. (2018). Moringa oleifera as a food fortificant: Recent trends and prospects. Journal of the Saudi Society of Agricultural Sciences, 17(2), 127-136. [CrossRef]
  • 45. Lin, Mengfei, Zhang, Junjie, & Chen, Xiaoyang. (2018). Bioactive flavonoids in Moringa oleifera and their health-promoting properties. Journal of Functional Foods, 47, 469-479. [CrossRef]
  • 46. Kumar, G., Giri, A., Arya, R., Tyagi, R., Mishra, S., Mishra, A. K., & Datta, J. . (2019). Multifaceted applications of different parts of Moringa species: Review of present status and future potentials. International Journal of Chemical Studies, 7(2), 835-842.
Toplam 44 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Eczacılık ve İlaç Bilimleri
Bölüm Derleme
Yazarlar

Burçin Mersin 0000-0002-4096-3202

Gülçin Saltan İşcan 0000-0001-6633-0713

Yayımlanma Tarihi 29 Mayıs 2022
Gönderilme Tarihi 9 Kasım 2021
Kabul Tarihi 1 Şubat 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 46 Sayı: 2

Kaynak Göster

APA Mersin, B., & Saltan İşcan, G. (2022). MORINGA OLEIFERA’NIN ETKİNLİK VE GÜVENLİĞİ. Journal of Faculty of Pharmacy of Ankara University, 46(2), 487-504. https://doi.org/10.33483/jfpau.1021227
AMA Mersin B, Saltan İşcan G. MORINGA OLEIFERA’NIN ETKİNLİK VE GÜVENLİĞİ. Ankara Ecz. Fak. Derg. Mayıs 2022;46(2):487-504. doi:10.33483/jfpau.1021227
Chicago Mersin, Burçin, ve Gülçin Saltan İşcan. “MORINGA OLEIFERA’NIN ETKİNLİK VE GÜVENLİĞİ”. Journal of Faculty of Pharmacy of Ankara University 46, sy. 2 (Mayıs 2022): 487-504. https://doi.org/10.33483/jfpau.1021227.
EndNote Mersin B, Saltan İşcan G (01 Mayıs 2022) MORINGA OLEIFERA’NIN ETKİNLİK VE GÜVENLİĞİ. Journal of Faculty of Pharmacy of Ankara University 46 2 487–504.
IEEE B. Mersin ve G. Saltan İşcan, “MORINGA OLEIFERA’NIN ETKİNLİK VE GÜVENLİĞİ”, Ankara Ecz. Fak. Derg., c. 46, sy. 2, ss. 487–504, 2022, doi: 10.33483/jfpau.1021227.
ISNAD Mersin, Burçin - Saltan İşcan, Gülçin. “MORINGA OLEIFERA’NIN ETKİNLİK VE GÜVENLİĞİ”. Journal of Faculty of Pharmacy of Ankara University 46/2 (Mayıs 2022), 487-504. https://doi.org/10.33483/jfpau.1021227.
JAMA Mersin B, Saltan İşcan G. MORINGA OLEIFERA’NIN ETKİNLİK VE GÜVENLİĞİ. Ankara Ecz. Fak. Derg. 2022;46:487–504.
MLA Mersin, Burçin ve Gülçin Saltan İşcan. “MORINGA OLEIFERA’NIN ETKİNLİK VE GÜVENLİĞİ”. Journal of Faculty of Pharmacy of Ankara University, c. 46, sy. 2, 2022, ss. 487-04, doi:10.33483/jfpau.1021227.
Vancouver Mersin B, Saltan İşcan G. MORINGA OLEIFERA’NIN ETKİNLİK VE GÜVENLİĞİ. Ankara Ecz. Fak. Derg. 2022;46(2):487-504.

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Kapsam ve Amaç

Ankara Üniversitesi Eczacılık Fakültesi Dergisi, açık erişim, hakemli bir dergi olup Türkçe veya İngilizce olarak farmasötik bilimler alanındaki önemli gelişmeleri içeren orijinal araştırmalar, derlemeler ve kısa bildiriler için uluslararası bir yayım ortamıdır. Bilimsel toplantılarda sunulan bildiriler supleman özel sayısı olarak dergide yayımlanabilir. Ayrıca, tüm farmasötik alandaki gelecek ve önceki ulusal ve uluslararası bilimsel toplantılar ile sosyal aktiviteleri içerir.