Araştırma Makalesi
BibTex RIS Kaynak Göster
Yıl 2022, Cilt: 6 Sayı: 2, 93 - 96, 31.12.2022
https://doi.org/10.32571/ijct.1148438

Öz

Antik çağlardan günümüze kadar bitkiler birçok farklı alanda kullanılmıştır. Bu kullanım alanlarının en dikkat çekenlerinden biri de alternatif tıptır. Türkiye hem konumu hem de diğer uygun koşullar bakımından bitkiler için zengin bir ülkedir. Bu zenginlik alternatif tıbbın önemini ortaya koymaktadır. Bu açıdan bitkilerin farmakolojik özelliklerinin belirlenmesi son derece gereklidir. Çalışmamızda Alyssum stylare (Boiss. & Balansa) Boiss'in toplam oksidan durumu (TOS), toplam antioksidan durumu (TAS), oksidatif stres indeksi (OSI) ve antimikrobiyal ajanlara karşı durumu incelenmiştir. Bitki örneğinin toprak üstü kısmı gerekli önlemler alınarak kurutulup toz haline getirildikten sonra ekstraksiyon yapılmıştır Etanol ekstraktı ve TOS, TAS, OSI verileri için Rel Assay kitleri tercih edilmiştir. Antimikrobiyal durumu, agar difüzyon yöntemi kullanılarak belirlendi. Çalışmamız sonucunda bitki ekstraktının TAS değeri 7.911±0.217 mmol/L, TOS değeri 11.587±0.202 µmol/L ve OSI değeri 0.146±0.001 olarak bulunmuştur. Standart bakteri suşlarına karşı 25-100 µg/mL ve mantar suşlarına karşı 200 µg/mL konsantrasyonda etkili olduğu belirlendi. Sonuç olarak A. stylare'in antioksidan ve antimikrobiyal açıdan çalışmalarda kullanılabileceği düşünülmektedir.

Kaynakça

  • Davies, K.J.A. International Union of Biochemistry and Molecular Biology Life, 2000, 50, 279-289.
  • Pellegrini, N.; Miglio, C.; Del Rio, D. International Journal of Food Sciences and Nutrition, 2009, 60, 12–22.
  • Mohammed, F. S.; Sevindik, M.; Bal, C.; Akgül, H.; Selamoglu, Z. Communications Faculty of Sciences University of Ankara Series C Biology, 2019,28, 128-142.
  • Michel, J.; Abd Rani, N. Z.; Husain, K. Frontiers in pharmacology, 2020, 11, 852.
  • Akhter, S.; Batool, A. I.; Selamoglu, Z.; Sevindik, M.; Eman, R.; Mustaqeem, M.; Aslam, M. Antibiotics, 2021, 10, 1011.
  • Mohammed, F. S.; Şabik, A. E.; Doğan, M.; Selamoğlu, Z.; Sevindik, M. Bulletin of Biotechnology, 2020, 1, 43-45.
  • Fitzgerald, M.; Heinrich, M.; Booker, A. Frontiers in pharmacology, 2020, 10, 1480.
  • Wang, W.; Xu, J.; Fang, H.; Li, Z.; Li, M. Plant Science, 2020, 298, 110573.
  • Krishnaiah, D.; Sarbatly, R.; Nithyanandam, R. Food and bioproducts processing, 2011, 89, 217-233.
  • Miastkowska, M.; Sikora, E. Cosmetics, 2018, 5, 55.
  • Pehlivan, M.; Mohammed, F. S.; Sevindik, M.; Akgul, H. Eurasian Journal of Forest Science, 2018, 6, 22-25.
  • Kına, E.; Uysal, İ.; Mohammed, F. S.; Doğan, M.; Sevindik, M. Turkish Journal of Agriculture-Food Science and Technology, 2021,9, 1905-1907.
  • Liaudanskas, M.; Žvikas, V.; Petrikaitė, V. Antioxidants, 2021, 10, 1115.
  • Mohammed, F. S.; Uysal, I.; Sevindik, M. Kadirli Uygulamalı Bilimler Fakültesi Dergisi, 2021, 1, 109-115.
  • Mohammed, F. S.; Korkmaz, N.; Doğan, M., Şabik, A. E.; Sevindik, M. Journal of Faculty of Pharmacy of Ankara University, 2021, 45, 524-534.
  • Shahbazi, R.; Sharifzad, F.; Bagheri, R.; Alsadi, N.; Yasavoli-Sharahi, H.; Matar, C. Nutrients, 2021, 13, 1516.
  • Unal, O.; Eraslan, E. C.; Uysal, I.; Mohammed, F. S.; Sevindik, M.; Akgul, H. Fresenius Environmental Bulletin, 2022, 31, 7341-7346.
  • Al-Shehbaz, I. A. J. Arn. Arbor., 1987, 68, 185–240.
  • Warwick, S.I.; Francis, A.; Al-Shehbaz, I.A. Plant Syst. Evol., 2006, 259, 249–258.
  • Bauer, A.W.; Kirby, W.M.; Sherris, J.C.; Turck, M. Am J Clin Pathol., 1966, 45, 493-96.
  • Hindler, J.; Hochstein, L.; Howell, A; Preparation of routine media and reagents used in antimicrobial susceptibility testing. Part 1. McFarland standards, p. 5.19.1-5.19.6. In H. D. Isenberg (ed) Clinical microbiology procedures handbook, vol. 1. American Society for Microbiology, Washington, D.C. USA, 1992.
  • Matuschek, E.; Brown, D.F.; Kahlmeter, G. Clin Microbiol Infect., 2014, 20, 255-266.
  • Erel, O. Clinical biochemistry, 2004, 37, 277-285.
  • Erel, O. Clinical biochemistry, 2005, 38, 1103-1111.
  • Sevindik, M. Fresenius Environmental Bulletin, 2019, 28, 3713-3717.
  • González-Lamothe, R.; Mitchell, G.; Gattuso, M.; Diarra, M. S.; Malouin, F.; Bouarab, K. International journal of molecular sciences, 2009, 10, 3400-3419.
  • Mohammed, F. S.; Akgul, H.; Sevindik, M.; Khaled, B. M. T. Fresenius Environmental Bulletin, 2018, 27, 5694-5702.
  • Tozyılmaz, V.; Ceylan, Y.; Bülbül, A.S. KSÜ Tarım ve Doğa Derg., 2021, 24,715-724.
  • Ozay, C.; Mammadov, R. Acta Biologica Hungarica, 2017, 8, 310–320.
  • Mohammed, F. S.; Pehlivan, M.; Sevindik, M. International Journal of Secondary Metabolite, 2019, 6, 317-322.
  • Mohammed, F. S.; Karakaş, M.; Akgül, H.; Sevindik, M. Fresen Environ Bull, 2019,28, 7419-7426.
  • Mohammed, F. S.; Günal, S.; Şabik, A. E.; Akgül, H., Sevindik, M. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, 2020, 23, 1114-1118.
  • Mohammed, F. S.; Kına, E.; Uysal, İ.; Mencik, K.; Dogan, M.; Pehlivan, M.; Sevindik, M. Turkish Journal of Agriculture-Food Science and Technology, 2022, 10, 1116-1119.
  • Sevindik, M.; Akgul, H.; Pehlivan, M.; Selamoglu, Z. Fresen Environ Bull., 2017, 26, 4757-4763.
  • Akgül, H.; Mohammed, F. S.; Kına, E.; Uysal, İ.; Sevindik, M.; Doğan, M. Turkish Journal of Agriculture-Food Science and Technology, 2022, 10, 272-275.
  • Uysal, İ.; Mohammed, F. S.; Şabik, A. E.; Kına, E.; Sevindik, M. Turkish Journal of Agriculture-Food Science and Technology, 2021, 9, 1902-1904.
  • Mohammed, F. S.; Daştan, T.; Sevindik, M.; Selamoğlu, Z. Cumhuriyet Medical Journal, 2019, 41, 558-562.
  • Mohammed, F. S.; Günal, S.; Pehlivan, M.; Doğan, M.; Sevindik, M.; Akgül, H. Gazi University Journal of Science, 2020, 33, 670-677.
  • Pehlivan, M.; Mohammed, F. S.; Şabik, A. E.; Kına, E.; Dogan, M.; Yumrutaş, Ö.; Sevindik, M. Some Turkish Journal of Agriculture-Food Science and Technology, 2021, 9, 1129-1132.
  • Mohammed, F. S.; Şabik, A. E.; Sevindik, E.; Pehlivan, M.; Sevindik, M. Turkish Journal of Agriculture-Food Science and Technology, 2020, 8,1171-1173.
  • Korkmaz, N.; Dayangaç, A.; Sevindik, M. J. Fac. Pharm. Ankara, 2021, 45, 554-564
  • Mohammed, F. S.; Kına, E.; Sevindik, M.; Doğan, M.; Pehlivan, M. Indian Journal of Natural Products and Resources Formerly Natural Product Radiance, 2021, 12, 459-462.
  • Akgül, H.; Korkmaz, N.; Dayangaç, A.; Sevindik, M. Turjaf, 2020, 8, 2222-2224.

Some pharmacological properties of Alyssum stylare (Boiss. & Balansa) Boiss

Yıl 2022, Cilt: 6 Sayı: 2, 93 - 96, 31.12.2022
https://doi.org/10.32571/ijct.1148438

Öz

From ancient times to the present, plants have been used in many different areas. One of the most striking of these areas is alternative medicine. Türkiye is a country rich for plants diversity both in terms of location and other favorable conditions. This diversity reveals the importance of alternative medicine. In this respect, it is extremely necessary to determine the pharmacological properties of plants. In our study, Alyssum stylare (Boiss. & Balansa) Boiss. total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI) as well as its status against antimicrobial agents were examined. After the above-ground part of the plant sample was dried and powdered by taking the necessary precautions, extraction was carried out Rel Assay kits were preferred for ethanol extract and TOS, TAS, OSI data. Its antimicrobial status was determined using the agar diffusion method. Consequently, of the study, the TAS capacity of the plant extract was 7.911±0.217 mmol/L, the TOS capacity was 11.587±0.202 µmol/L, and the OSI capacity was 0.146±0.001. It was used that it was effective against standard bacteria strains at 25-100 µg/mL and 200 µg/mL concentrations against fungi strains. Consequently, it is thought that A. stylare can be used in studies conducted for antioxidant and antimicrobial.

Kaynakça

  • Davies, K.J.A. International Union of Biochemistry and Molecular Biology Life, 2000, 50, 279-289.
  • Pellegrini, N.; Miglio, C.; Del Rio, D. International Journal of Food Sciences and Nutrition, 2009, 60, 12–22.
  • Mohammed, F. S.; Sevindik, M.; Bal, C.; Akgül, H.; Selamoglu, Z. Communications Faculty of Sciences University of Ankara Series C Biology, 2019,28, 128-142.
  • Michel, J.; Abd Rani, N. Z.; Husain, K. Frontiers in pharmacology, 2020, 11, 852.
  • Akhter, S.; Batool, A. I.; Selamoglu, Z.; Sevindik, M.; Eman, R.; Mustaqeem, M.; Aslam, M. Antibiotics, 2021, 10, 1011.
  • Mohammed, F. S.; Şabik, A. E.; Doğan, M.; Selamoğlu, Z.; Sevindik, M. Bulletin of Biotechnology, 2020, 1, 43-45.
  • Fitzgerald, M.; Heinrich, M.; Booker, A. Frontiers in pharmacology, 2020, 10, 1480.
  • Wang, W.; Xu, J.; Fang, H.; Li, Z.; Li, M. Plant Science, 2020, 298, 110573.
  • Krishnaiah, D.; Sarbatly, R.; Nithyanandam, R. Food and bioproducts processing, 2011, 89, 217-233.
  • Miastkowska, M.; Sikora, E. Cosmetics, 2018, 5, 55.
  • Pehlivan, M.; Mohammed, F. S.; Sevindik, M.; Akgul, H. Eurasian Journal of Forest Science, 2018, 6, 22-25.
  • Kına, E.; Uysal, İ.; Mohammed, F. S.; Doğan, M.; Sevindik, M. Turkish Journal of Agriculture-Food Science and Technology, 2021,9, 1905-1907.
  • Liaudanskas, M.; Žvikas, V.; Petrikaitė, V. Antioxidants, 2021, 10, 1115.
  • Mohammed, F. S.; Uysal, I.; Sevindik, M. Kadirli Uygulamalı Bilimler Fakültesi Dergisi, 2021, 1, 109-115.
  • Mohammed, F. S.; Korkmaz, N.; Doğan, M., Şabik, A. E.; Sevindik, M. Journal of Faculty of Pharmacy of Ankara University, 2021, 45, 524-534.
  • Shahbazi, R.; Sharifzad, F.; Bagheri, R.; Alsadi, N.; Yasavoli-Sharahi, H.; Matar, C. Nutrients, 2021, 13, 1516.
  • Unal, O.; Eraslan, E. C.; Uysal, I.; Mohammed, F. S.; Sevindik, M.; Akgul, H. Fresenius Environmental Bulletin, 2022, 31, 7341-7346.
  • Al-Shehbaz, I. A. J. Arn. Arbor., 1987, 68, 185–240.
  • Warwick, S.I.; Francis, A.; Al-Shehbaz, I.A. Plant Syst. Evol., 2006, 259, 249–258.
  • Bauer, A.W.; Kirby, W.M.; Sherris, J.C.; Turck, M. Am J Clin Pathol., 1966, 45, 493-96.
  • Hindler, J.; Hochstein, L.; Howell, A; Preparation of routine media and reagents used in antimicrobial susceptibility testing. Part 1. McFarland standards, p. 5.19.1-5.19.6. In H. D. Isenberg (ed) Clinical microbiology procedures handbook, vol. 1. American Society for Microbiology, Washington, D.C. USA, 1992.
  • Matuschek, E.; Brown, D.F.; Kahlmeter, G. Clin Microbiol Infect., 2014, 20, 255-266.
  • Erel, O. Clinical biochemistry, 2004, 37, 277-285.
  • Erel, O. Clinical biochemistry, 2005, 38, 1103-1111.
  • Sevindik, M. Fresenius Environmental Bulletin, 2019, 28, 3713-3717.
  • González-Lamothe, R.; Mitchell, G.; Gattuso, M.; Diarra, M. S.; Malouin, F.; Bouarab, K. International journal of molecular sciences, 2009, 10, 3400-3419.
  • Mohammed, F. S.; Akgul, H.; Sevindik, M.; Khaled, B. M. T. Fresenius Environmental Bulletin, 2018, 27, 5694-5702.
  • Tozyılmaz, V.; Ceylan, Y.; Bülbül, A.S. KSÜ Tarım ve Doğa Derg., 2021, 24,715-724.
  • Ozay, C.; Mammadov, R. Acta Biologica Hungarica, 2017, 8, 310–320.
  • Mohammed, F. S.; Pehlivan, M.; Sevindik, M. International Journal of Secondary Metabolite, 2019, 6, 317-322.
  • Mohammed, F. S.; Karakaş, M.; Akgül, H.; Sevindik, M. Fresen Environ Bull, 2019,28, 7419-7426.
  • Mohammed, F. S.; Günal, S.; Şabik, A. E.; Akgül, H., Sevindik, M. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, 2020, 23, 1114-1118.
  • Mohammed, F. S.; Kına, E.; Uysal, İ.; Mencik, K.; Dogan, M.; Pehlivan, M.; Sevindik, M. Turkish Journal of Agriculture-Food Science and Technology, 2022, 10, 1116-1119.
  • Sevindik, M.; Akgul, H.; Pehlivan, M.; Selamoglu, Z. Fresen Environ Bull., 2017, 26, 4757-4763.
  • Akgül, H.; Mohammed, F. S.; Kına, E.; Uysal, İ.; Sevindik, M.; Doğan, M. Turkish Journal of Agriculture-Food Science and Technology, 2022, 10, 272-275.
  • Uysal, İ.; Mohammed, F. S.; Şabik, A. E.; Kına, E.; Sevindik, M. Turkish Journal of Agriculture-Food Science and Technology, 2021, 9, 1902-1904.
  • Mohammed, F. S.; Daştan, T.; Sevindik, M.; Selamoğlu, Z. Cumhuriyet Medical Journal, 2019, 41, 558-562.
  • Mohammed, F. S.; Günal, S.; Pehlivan, M.; Doğan, M.; Sevindik, M.; Akgül, H. Gazi University Journal of Science, 2020, 33, 670-677.
  • Pehlivan, M.; Mohammed, F. S.; Şabik, A. E.; Kına, E.; Dogan, M.; Yumrutaş, Ö.; Sevindik, M. Some Turkish Journal of Agriculture-Food Science and Technology, 2021, 9, 1129-1132.
  • Mohammed, F. S.; Şabik, A. E.; Sevindik, E.; Pehlivan, M.; Sevindik, M. Turkish Journal of Agriculture-Food Science and Technology, 2020, 8,1171-1173.
  • Korkmaz, N.; Dayangaç, A.; Sevindik, M. J. Fac. Pharm. Ankara, 2021, 45, 554-564
  • Mohammed, F. S.; Kına, E.; Sevindik, M.; Doğan, M.; Pehlivan, M. Indian Journal of Natural Products and Resources Formerly Natural Product Radiance, 2021, 12, 459-462.
  • Akgül, H.; Korkmaz, N.; Dayangaç, A.; Sevindik, M. Turjaf, 2020, 8, 2222-2224.
Toplam 43 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Yapısal Biyoloji
Bölüm Makale
Yazarlar

İmran Uysal 0000-0003-0942-9658

Yayımlanma Tarihi 31 Aralık 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 6 Sayı: 2

Kaynak Göster

APA Uysal, İ. (2022). Some pharmacological properties of Alyssum stylare (Boiss. & Balansa) Boiss. International Journal of Chemistry and Technology, 6(2), 93-96. https://doi.org/10.32571/ijct.1148438
AMA Uysal İ. Some pharmacological properties of Alyssum stylare (Boiss. & Balansa) Boiss. Int. J. Chem. Technol. Aralık 2022;6(2):93-96. doi:10.32571/ijct.1148438
Chicago Uysal, İmran. “Some Pharmacological Properties of Alyssum Stylare (Boiss. & Balansa) Boiss”. International Journal of Chemistry and Technology 6, sy. 2 (Aralık 2022): 93-96. https://doi.org/10.32571/ijct.1148438.
EndNote Uysal İ (01 Aralık 2022) Some pharmacological properties of Alyssum stylare (Boiss. & Balansa) Boiss. International Journal of Chemistry and Technology 6 2 93–96.
IEEE İ. Uysal, “Some pharmacological properties of Alyssum stylare (Boiss. & Balansa) Boiss”, Int. J. Chem. Technol., c. 6, sy. 2, ss. 93–96, 2022, doi: 10.32571/ijct.1148438.
ISNAD Uysal, İmran. “Some Pharmacological Properties of Alyssum Stylare (Boiss. & Balansa) Boiss”. International Journal of Chemistry and Technology 6/2 (Aralık 2022), 93-96. https://doi.org/10.32571/ijct.1148438.
JAMA Uysal İ. Some pharmacological properties of Alyssum stylare (Boiss. & Balansa) Boiss. Int. J. Chem. Technol. 2022;6:93–96.
MLA Uysal, İmran. “Some Pharmacological Properties of Alyssum Stylare (Boiss. & Balansa) Boiss”. International Journal of Chemistry and Technology, c. 6, sy. 2, 2022, ss. 93-96, doi:10.32571/ijct.1148438.
Vancouver Uysal İ. Some pharmacological properties of Alyssum stylare (Boiss. & Balansa) Boiss. Int. J. Chem. Technol. 2022;6(2):93-6.