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RANUNCULUS SERICEUS BANKS & SOL. EXTRACT FRACTIONS POSSESS ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY

Yıl 2018, Cilt: 4 Sayı: 1, 9 - 15, 31.05.2018

Hakan Atcı Yalçın Karagöz

Öz

Ranunculus sericeus, collected from Ağrı, was successively extracted with n-hexane,
chloroform, acetone and methanol, in a Soxhlet extractor. Obtained extracts
were tested for antibacterial activity against human and plant pathogenic
bacteria Pseudomonas aeruginosa, Bacillus
subtilis, Staphylococcus aureus, Enterococcus
faecalis, Xanthomonas axonopodis pv.
vitians, Enterobacter cloacae, Burkholderia sepasia, Pantoea ananatis, and
for antifungal activity against fungi Rhizoctonia
sp., Alternaria sp., and
Fusarium sp. Minimum Inhibitory
Concentration (MIC) values were determined. Our results indicate that acetone
and methanol fractions have moderate antibacterial and antifungal activity.

Anahtar Kelimeler

Ranunculus sericeus antibacterial activity antifungal activity extract fractions

Kaynakça

  • AKBULUT, S., SEMUR, H., KOSE, O., OZHASENEKLER, A., CELIKTAS, M., BASBUG, M. AND YAGMUR, Y. (2011), Phytocontact dermatitis due to Ranunculus arvensis mimicking burn injury: report of three cases and literature review, Int J Emerg Med, 4, 7.
  • AKKOL, E. K., SUNTAR, I., ERDOGAN, T. F., KELES, H., GONENC, T. M. AND KIVCAK, B. (2012), Wound healing and anti-inflammatory properties of Ranunculus pedatus and Ranunculus constantinapolitanus: a comparative study, J Ethnopharmacol, 139, 478-484.
  • ASLAM, M., A. CHOUDHARY, B., UZAIR, M. AND SUBHAN IJAZ, A. (2012), The genus Ranunculus: A phytochemical and ethnopharmacological review, International Journal of Pharmacy and Pharmaceutical Sciences, 4, 15-22.
  • BARBOUR, E. K., AL SHARIF, M., SAGHERIAN, V. K., HABRE, A. N., TALHOUK, R. S. AND TALHOUK, S. N. (2004), Screening of selected indigenous plants of Lebanon for antimicrobial activity, J Ethnopharmacol, 93, 1-7.
  • BHATTI, M. Z., ALI, A., AHMAD, A., SAEED, A. AND MALIK, S. A. (2015a), Antioxidant and phytochemical analysis of Ranunculus arvensis L. extracts, BMC Res Notes, 8, 279.
  • BHATTI, M. Z., ALI, A., SAEED, A., SAEED, A. AND MALIK, S. A. (2015b), Antimicrobial, antitumor and brine shrimp lethality assay of Ranunculus arvensis L. extracts, Pak J Pharm Sci, 28, 945-949.
  • BOROOMAND, N., SADAT-HOSSEINI, M., MOGHBELI, M. AND FARAJPOUR, M. (2018), Phytochemical components, total phenol and mineral contents and antioxidant activity of six major medicinal plants from Rayen, Iran, Nat Prod Res, 32, 564-567.
  • BUKOWIECKI, H. AND ZAREBSKA, I. (1966a), [Antibiotic activity of protoanemonin in extracts of some lowland species of Ranunculus L], Acta Pol Pharm, 23, 163-167.
  • BUKOWIECKI, H. AND ZAREBSKA, I. (1966b), [Structure of the vegetative organs of the species Ranunculus lanuginosus L. and of some ranunculi plants with antibiotic activity], Acta Pol Pharm, 23, 159-162.
  • CALKA, O., AKDENIZ, N., OZKOL, H. U., KARADAG, A. S. AND BEHCET, L. (2011), Irritant contact dermatitis caused by Ranunculus kotschyi Boiss in 6 cases, Contact Dermatitis, 64, 174-176.
  • CAO, B. J., MENG, Q. Y. AND JI, N. (1992), Analgesic and anti-inflammatory effects of Ranunculus japonicus extract, Planta Med, 58, 496-498.
  • DAI, H. L., JIA, G. Z. AND ZHAO, S. (2015), Total glycosides of Ranunculus japonius prevent hypertrophy in cardiomyocytes via alleviating chronic Ca(2+) overload, Chin Med Sci J, 30, 37-43.
  • DAVIS, P. H., CULLEN, J. AND COODE, M. J. E. (1965), Flora of Turkey and the East Aegean Islands (Edinburgh,: University Press)
  • DENG, K. Z., XIONG, Y., ZHOU, B., GUAN, Y. M. AND LUO, Y. M. (2013), Chemical constituents from the roots of Ranunculus ternatus and their inhibitory effects on Mycobacterium tuberculosis, Molecules, 18, 11859-11865.
  • FOSTOK, S. F., EZZEDDINE, R. A., HOMAIDAN, F. R., AL-SAGHIR, J. A., SALLOUM, R. G., SALIBA, N. A. AND TALHOUK, R. S. (2009), Interleukin-6 and Cyclooxygenase-2 downregulation by fatty-acid fractions of Ranunculus constantinopolitanus, BMC Complement Altern Med, 9, 44.
  • GAO, X. W., LIU, Y., YANG, Z. C. AND TAN, Y. Z. (2014), [Protective effect of total glycosides of Ranunculus japonicus on myocardial ischemic-reperfusion injury in isolated rat hearts], Zhong Yao Cai, 37, 1429-1433.
  • KARAMAN, I., SAHIN, F., GULLUCE, M., OGUTCU, H., SENGUL, M. AND ADIGUZEL, A. (2003), Antimicrobial activity of aqueous and methanol extracts of Juniperus oxycedrus L, J Ethnopharmacol, 85, 231-235.
  • KHAN, F. A., ZAHOOR, M. AND KHAN, E. (2016), Chemical and biological evaluation of Ranunculus muricatus, Pak J Pharm Sci, 29, 503-510.
  • KOSE, R., OKUR, M. I., BINGOL, I. AND CETIN, H. (2008), Phytocontact dermatitis mimicking a burn injury due to Ranunculus constantinopolitanus, Contact Dermatitis, 59, 249-250.
  • LORIMER, S. D., BARNS, G., EVANS, A. C., FOSTER, L. M., MAY, B. C., PERRY, N. B. AND TANGNEY, R. S. (1996), Cytotoxicity and antimicrobial activity of plants from New Zealand's subantarctic islands, Phytomedicine, 2, 317-323.
  • LV, X., WANG, H., HAN, H., LV, S. AND QIN, D. (2010), [Effects of polysaccharide of radix ranunculi ternati on immunomodulation and anti-oxidation], Zhongguo Zhong Yao Za Zhi, 35, 1862-1865.
  • MILANESI, N., D'ERME, A. M. AND GOLA, M. (2015), De rerum natura: a case of irritant phytodermatitis from Ranunculus bulbosus, Int J Dermatol, 54, 202-203.
  • MISRA, S. B. AND DIXIT, S. N. (1978), Antifungal properties of leaf extract of Ranunculus sceleratus L, Experientia, 34, 1442-1443.
  • MURRAY, P. R. (1995), Manual of clinical microbiology (6th ed.; Washington, D.C.: ASM Press)
  • OZKOL, H. U., CALKA, O., AKDENIZ, N. AND PINAR, S. M. (2014), Phytodermatitis in eastern Turkey: a retrospective, observational study, Dermatitis, 25, 140-146.
  • POLAT, M. (2016), A case of phytodermatitis due to Ranunculus arvensis used as an herbal remedy, Int J Dermatol, 55, e37-38.
  • POLAT, M., OZTAS, P., YALCIN, B., TAMER, E., GUR, G. AND ALLI, N. (2007), Contact dermatitis due to Allivum sativum and Ranunculus illyricus: two cases, Contact Dermatitis, 57, 279-280.
  • PRIETO, J. M., RECIO, M. C., GINER, R. M., SCHINELLA, G. R., MANEZ, S. AND RIOS, J. L. (2008), In vitro and in vivo effects of Ranunculus peltatus subsp. baudotii methanol extract on models of eicosanoid production and contact dermatitis, Phytother Res, 22, 297-302.
  • RAZIQ, N., SAEED, M., ALI, M. S., ZAFAR, S., SHAHID, M. AND LATEEF, M. (2017), A new glycosidic antioxidant from Ranunculus muricatus L. (Ranunculaceae) exhibited lipoxygenasae and xanthine oxidase inhibition properties, Nat Prod Res, 31, 1251-1257.
  • SAHIN, F., KARAMAN, I., GULLUCE, M., OGUTCU, H., SENGUL, M., ADIGUZEL, A., OZTURK, S. AND KOTAN, R. (2003), Evaluation of antimicrobial activities of Satureja hortensis L, J Ethnopharmacol, 87, 61-65.
  • SEZIK, E., YEŞILADA, E., TABATA, M., GISHO, H., TAKAISHI, Y., FUJITA, T., TOSHIHIRO, T. AND TAKEDA, Y. (1997), Traditional Medicine in Turkey VIII. Folk Medicine in East Anatolia; Erzurum, Erzincan, Ağri, Kars, Iğdir Provinces, Economic Botany, 51, 195-211.
  • Türkiye İlaç ve Tıbbi Cihaz Kurumu, Tıbbi Bitki Listesi. Accessed: 06.04.2018. http://www.titck.gov.tr/T%C4%B1bbiBitkiListesi?PageNo=10.
  • TORRES, M. J., BRANDAN, C. P., SABATE, D. C., PETROSELLI, G., ERRA-BALSELLS, R. AND AUDISIO, M. C. (2017), Biological activity of the lipopeptide-producing Bacillus amyloliquefaciens PGPBacCA1 on common bean Phaseolus vulgaris L. pathogens, Biological Control, 105, 93-99.
  • UCMAK, D., AYHAN, E., MELTEM AKKURT, Z. AND HAYDAR, U. (2014), Presentation of three cases with phyto contact dermatitis caused by Ranunculus and Anthemis genera, J Dermatolog Treat, 25, 467-469.
  • UMAIR, M., ALTAF, M. AND ABBASI, A. M. (2017), An ethnobotanical survey of indigenous medicinal plants in Hafizabad district, Punjab-Pakistan, PLoS One, 12, e0177912.
  • WHO, WHO publishes list of bacteria for which new antibiotics are urgently needed. Accessed: 06.04.2018. http://www.who.int/mediacentre/news/releases/2017/bacteria-antibiotics-needed/en/.
  • ZHOU, L., ZHANG, W. AND XU, J. (1995), [Effect of the active components of Ranunculus ternatus Thunb. on the inductive production of tumor necrosis factors by macrophages], Zhongguo Yi Xue Ke Xue Yuan Xue Bao, 17, 456-460.

Yıl 2018, Cilt: 4 Sayı: 1, 9 - 15, 31.05.2018

Hakan Atcı Yalçın Karagöz

Öz

Kaynakça

  • AKBULUT, S., SEMUR, H., KOSE, O., OZHASENEKLER, A., CELIKTAS, M., BASBUG, M. AND YAGMUR, Y. (2011), Phytocontact dermatitis due to Ranunculus arvensis mimicking burn injury: report of three cases and literature review, Int J Emerg Med, 4, 7.
  • AKKOL, E. K., SUNTAR, I., ERDOGAN, T. F., KELES, H., GONENC, T. M. AND KIVCAK, B. (2012), Wound healing and anti-inflammatory properties of Ranunculus pedatus and Ranunculus constantinapolitanus: a comparative study, J Ethnopharmacol, 139, 478-484.
  • ASLAM, M., A. CHOUDHARY, B., UZAIR, M. AND SUBHAN IJAZ, A. (2012), The genus Ranunculus: A phytochemical and ethnopharmacological review, International Journal of Pharmacy and Pharmaceutical Sciences, 4, 15-22.
  • BARBOUR, E. K., AL SHARIF, M., SAGHERIAN, V. K., HABRE, A. N., TALHOUK, R. S. AND TALHOUK, S. N. (2004), Screening of selected indigenous plants of Lebanon for antimicrobial activity, J Ethnopharmacol, 93, 1-7.
  • BHATTI, M. Z., ALI, A., AHMAD, A., SAEED, A. AND MALIK, S. A. (2015a), Antioxidant and phytochemical analysis of Ranunculus arvensis L. extracts, BMC Res Notes, 8, 279.
  • BHATTI, M. Z., ALI, A., SAEED, A., SAEED, A. AND MALIK, S. A. (2015b), Antimicrobial, antitumor and brine shrimp lethality assay of Ranunculus arvensis L. extracts, Pak J Pharm Sci, 28, 945-949.
  • BOROOMAND, N., SADAT-HOSSEINI, M., MOGHBELI, M. AND FARAJPOUR, M. (2018), Phytochemical components, total phenol and mineral contents and antioxidant activity of six major medicinal plants from Rayen, Iran, Nat Prod Res, 32, 564-567.
  • BUKOWIECKI, H. AND ZAREBSKA, I. (1966a), [Antibiotic activity of protoanemonin in extracts of some lowland species of Ranunculus L], Acta Pol Pharm, 23, 163-167.
  • BUKOWIECKI, H. AND ZAREBSKA, I. (1966b), [Structure of the vegetative organs of the species Ranunculus lanuginosus L. and of some ranunculi plants with antibiotic activity], Acta Pol Pharm, 23, 159-162.
  • CALKA, O., AKDENIZ, N., OZKOL, H. U., KARADAG, A. S. AND BEHCET, L. (2011), Irritant contact dermatitis caused by Ranunculus kotschyi Boiss in 6 cases, Contact Dermatitis, 64, 174-176.
  • CAO, B. J., MENG, Q. Y. AND JI, N. (1992), Analgesic and anti-inflammatory effects of Ranunculus japonicus extract, Planta Med, 58, 496-498.
  • DAI, H. L., JIA, G. Z. AND ZHAO, S. (2015), Total glycosides of Ranunculus japonius prevent hypertrophy in cardiomyocytes via alleviating chronic Ca(2+) overload, Chin Med Sci J, 30, 37-43.
  • DAVIS, P. H., CULLEN, J. AND COODE, M. J. E. (1965), Flora of Turkey and the East Aegean Islands (Edinburgh,: University Press)
  • DENG, K. Z., XIONG, Y., ZHOU, B., GUAN, Y. M. AND LUO, Y. M. (2013), Chemical constituents from the roots of Ranunculus ternatus and their inhibitory effects on Mycobacterium tuberculosis, Molecules, 18, 11859-11865.
  • FOSTOK, S. F., EZZEDDINE, R. A., HOMAIDAN, F. R., AL-SAGHIR, J. A., SALLOUM, R. G., SALIBA, N. A. AND TALHOUK, R. S. (2009), Interleukin-6 and Cyclooxygenase-2 downregulation by fatty-acid fractions of Ranunculus constantinopolitanus, BMC Complement Altern Med, 9, 44.
  • GAO, X. W., LIU, Y., YANG, Z. C. AND TAN, Y. Z. (2014), [Protective effect of total glycosides of Ranunculus japonicus on myocardial ischemic-reperfusion injury in isolated rat hearts], Zhong Yao Cai, 37, 1429-1433.
  • KARAMAN, I., SAHIN, F., GULLUCE, M., OGUTCU, H., SENGUL, M. AND ADIGUZEL, A. (2003), Antimicrobial activity of aqueous and methanol extracts of Juniperus oxycedrus L, J Ethnopharmacol, 85, 231-235.
  • KHAN, F. A., ZAHOOR, M. AND KHAN, E. (2016), Chemical and biological evaluation of Ranunculus muricatus, Pak J Pharm Sci, 29, 503-510.
  • KOSE, R., OKUR, M. I., BINGOL, I. AND CETIN, H. (2008), Phytocontact dermatitis mimicking a burn injury due to Ranunculus constantinopolitanus, Contact Dermatitis, 59, 249-250.
  • LORIMER, S. D., BARNS, G., EVANS, A. C., FOSTER, L. M., MAY, B. C., PERRY, N. B. AND TANGNEY, R. S. (1996), Cytotoxicity and antimicrobial activity of plants from New Zealand's subantarctic islands, Phytomedicine, 2, 317-323.
  • LV, X., WANG, H., HAN, H., LV, S. AND QIN, D. (2010), [Effects of polysaccharide of radix ranunculi ternati on immunomodulation and anti-oxidation], Zhongguo Zhong Yao Za Zhi, 35, 1862-1865.
  • MILANESI, N., D'ERME, A. M. AND GOLA, M. (2015), De rerum natura: a case of irritant phytodermatitis from Ranunculus bulbosus, Int J Dermatol, 54, 202-203.
  • MISRA, S. B. AND DIXIT, S. N. (1978), Antifungal properties of leaf extract of Ranunculus sceleratus L, Experientia, 34, 1442-1443.
  • MURRAY, P. R. (1995), Manual of clinical microbiology (6th ed.; Washington, D.C.: ASM Press)
  • OZKOL, H. U., CALKA, O., AKDENIZ, N. AND PINAR, S. M. (2014), Phytodermatitis in eastern Turkey: a retrospective, observational study, Dermatitis, 25, 140-146.
  • POLAT, M. (2016), A case of phytodermatitis due to Ranunculus arvensis used as an herbal remedy, Int J Dermatol, 55, e37-38.
  • POLAT, M., OZTAS, P., YALCIN, B., TAMER, E., GUR, G. AND ALLI, N. (2007), Contact dermatitis due to Allivum sativum and Ranunculus illyricus: two cases, Contact Dermatitis, 57, 279-280.
  • PRIETO, J. M., RECIO, M. C., GINER, R. M., SCHINELLA, G. R., MANEZ, S. AND RIOS, J. L. (2008), In vitro and in vivo effects of Ranunculus peltatus subsp. baudotii methanol extract on models of eicosanoid production and contact dermatitis, Phytother Res, 22, 297-302.
  • RAZIQ, N., SAEED, M., ALI, M. S., ZAFAR, S., SHAHID, M. AND LATEEF, M. (2017), A new glycosidic antioxidant from Ranunculus muricatus L. (Ranunculaceae) exhibited lipoxygenasae and xanthine oxidase inhibition properties, Nat Prod Res, 31, 1251-1257.
  • SAHIN, F., KARAMAN, I., GULLUCE, M., OGUTCU, H., SENGUL, M., ADIGUZEL, A., OZTURK, S. AND KOTAN, R. (2003), Evaluation of antimicrobial activities of Satureja hortensis L, J Ethnopharmacol, 87, 61-65.
  • SEZIK, E., YEŞILADA, E., TABATA, M., GISHO, H., TAKAISHI, Y., FUJITA, T., TOSHIHIRO, T. AND TAKEDA, Y. (1997), Traditional Medicine in Turkey VIII. Folk Medicine in East Anatolia; Erzurum, Erzincan, Ağri, Kars, Iğdir Provinces, Economic Botany, 51, 195-211.
  • Türkiye İlaç ve Tıbbi Cihaz Kurumu, Tıbbi Bitki Listesi. Accessed: 06.04.2018. http://www.titck.gov.tr/T%C4%B1bbiBitkiListesi?PageNo=10.
  • TORRES, M. J., BRANDAN, C. P., SABATE, D. C., PETROSELLI, G., ERRA-BALSELLS, R. AND AUDISIO, M. C. (2017), Biological activity of the lipopeptide-producing Bacillus amyloliquefaciens PGPBacCA1 on common bean Phaseolus vulgaris L. pathogens, Biological Control, 105, 93-99.
  • UCMAK, D., AYHAN, E., MELTEM AKKURT, Z. AND HAYDAR, U. (2014), Presentation of three cases with phyto contact dermatitis caused by Ranunculus and Anthemis genera, J Dermatolog Treat, 25, 467-469.
  • UMAIR, M., ALTAF, M. AND ABBASI, A. M. (2017), An ethnobotanical survey of indigenous medicinal plants in Hafizabad district, Punjab-Pakistan, PLoS One, 12, e0177912.
  • WHO, WHO publishes list of bacteria for which new antibiotics are urgently needed. Accessed: 06.04.2018. http://www.who.int/mediacentre/news/releases/2017/bacteria-antibiotics-needed/en/.
  • ZHOU, L., ZHANG, W. AND XU, J. (1995), [Effect of the active components of Ranunculus ternatus Thunb. on the inductive production of tumor necrosis factors by macrophages], Zhongguo Yi Xue Ke Xue Yuan Xue Bao, 17, 456-460.
Toplam 37 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Makaleler
Yazarlar

Hakan Atcı Bu kişi benim

Yalçın Karagöz

Yayımlanma Tarihi 31 Mayıs 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 4 Sayı: 1

Kaynak Göster

APA Atcı, H., & Karagöz, Y. (2018). RANUNCULUS SERICEUS BANKS & SOL. EXTRACT FRACTIONS POSSESS ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY. Eastern Anatolian Journal of Science, 4(1), 9-15.
AMA Atcı H, Karagöz Y. RANUNCULUS SERICEUS BANKS & SOL. EXTRACT FRACTIONS POSSESS ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY. Eastern Anatolian Journal of Science. Mayıs 2018;4(1):9-15.
Chicago Atcı, Hakan, ve Yalçın Karagöz. “RANUNCULUS SERICEUS BANKS & SOL. EXTRACT FRACTIONS POSSESS ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY”. Eastern Anatolian Journal of Science 4, sy. 1 (Mayıs 2018): 9-15.
EndNote Atcı H, Karagöz Y (01 Mayıs 2018) RANUNCULUS SERICEUS BANKS & SOL. EXTRACT FRACTIONS POSSESS ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY. Eastern Anatolian Journal of Science 4 1 9–15.
IEEE H. Atcı ve Y. Karagöz, “RANUNCULUS SERICEUS BANKS & SOL. EXTRACT FRACTIONS POSSESS ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY”, Eastern Anatolian Journal of Science, c. 4, sy. 1, ss. 9–15, 2018.
ISNAD Atcı, Hakan - Karagöz, Yalçın. “RANUNCULUS SERICEUS BANKS & SOL. EXTRACT FRACTIONS POSSESS ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY”. Eastern Anatolian Journal of Science 4/1 (Mayıs 2018), 9-15.
JAMA Atcı H, Karagöz Y. RANUNCULUS SERICEUS BANKS & SOL. EXTRACT FRACTIONS POSSESS ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY. Eastern Anatolian Journal of Science. 2018;4:9–15.
MLA Atcı, Hakan ve Yalçın Karagöz. “RANUNCULUS SERICEUS BANKS & SOL. EXTRACT FRACTIONS POSSESS ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY”. Eastern Anatolian Journal of Science, c. 4, sy. 1, 2018, ss. 9-15.
Vancouver Atcı H, Karagöz Y. RANUNCULUS SERICEUS BANKS & SOL. EXTRACT FRACTIONS POSSESS ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY. Eastern Anatolian Journal of Science. 2018;4(1):9-15.