Research Article
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Year 2023, Volume: 11 Issue: 2, 244 - 252, 31.08.2023

Önder Özen Onur Köse

https://doi.org/10.24998/maeusabed.1340953

Abstract

Supporting Institution

Burdur Mehmet Akif Ersoy Üniversitesi Bilimsel Araştırma Projeleri Koordinatörlüğü

Project Number

0753-YL-21

References

  • Akhoundi, M., Kuhls, K., Cannet, A., Votýpka, J., Marty, P., Delaunay, P., Sereno, D., 2016. A historical overview of the classification, evolution, and dispersion of Leishmania parasites and sandflies. PLoS Neglected Tropical Diseases 10, 1-40.
  • Akman, L., Aksu, H.S., Wang, R.Q., Özensoy, S., Özbel, Y., Alkan, Z., Özcel, M.A., Çulha, G., Özcan, K., Uzun, S., Memişoglu, H.R., Chang, K.P., 2000. Multi-site DNA polymorphism analyses of Leishmania isolates define their genotypes predicting clinical epidemiology of leishmaniasis in a specific region. Journal of Eukaryotic Microbiology 47, 545-554.
  • Alemayehu, B., Alemayehu, M., 2017. Leishmaniasis: A Review on Parasite, Vector and Reservoir Host. Health Science Journal 11, 519.
  • Andrade, H.M., Reis, A.B., Santos, S.L., Volpini, A.C., Marques, M.J., Romanha, A.J., 2006. Use of PCR-RFLP to identify Leishmania species in naturally-infected dogs. Veterinary Parasitology 140, 231-238.
  • Aslan Çelik, B., Şahin, T., Çelik, Ö., 2019. Retrospective Evaluation of Canine Leishmaniasis in Turkey. Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi 33, 123-130.
  • Aydenizöz, M., Yağcı, B.B., Taylan Özkan, A., Duru, S.Y., Gazyağcı, A.N., 2010. Investigation of the prevalence of visceral leishmaniasis by the microculture method and IFAT in dogs in Kırıkkale. Türkiye Parazitoloji Dergisi 34, 1-5.
  • Ayele, A., Seyoum, Z., 2016. A Review on Canine Leishmaniasis; Etiology, Clinical Sign, Pathogenesis, Treatment and Control Methods. Global Veterinaria 17, 343-352.
  • Bakırcı, S., Bilgiç, H.B., Köse, O., Aksulu, A., Hacılarlıoğlu, S., Erdoğan, H., Karagenç, T., 2016. Molecular and seroprevalence of canine visceral leishmaniasis in West Anatolia, Turkey. Turkish Journal of Veterinary and Animal Sciences 40, 637-644.
  • Bakırcı, S., Topçuoğlu, A.D., 2021. Molecular and Serological Analysis for Prevalence of Canine Visceral Leishmaniasis in the Muğla Region of Turkey. Türkiye Parazitoloji Dergisi 45, 11-16.
  • Bamorovat, M., Sharifi, I., Dabiri, S., Mohammadi, M.A., Harandi, M.F., Mohebali, M., Aflatoonian, M.R., Keyhani, A., 2015. Leishmania tropica in Stray Dogs in Southeast Iran. Iranian Journal of Public Health 44, 1359-1366.
  • Baneth, G., Koutinas, A.F., Solano-Gallego, L., Bourdeau, P., Ferrer, L., 2008. Canine leishmaniosis – new concepts and insights on an expanding zoonosis: part one. Trends in Parasitology 24, 324-330.
  • Baneth, G., Zivotofsky, D., Nachum-Biala, Y., Yasur-Landau, D., Botero, A.M., 2014. Mucocutaneous Leishmania tropica infection in a dog from a human cutaneous leishmaniasis focus. Parasites and Vectors 7, 1-5.
  • Baneth, G., Yasur-Landau, D., Gilad, M., Nachum-Biala, Y., 2017. Canine leishmaniosis caused by Leishmania major and Leishmania tropica: comparative findings and serology. Parasites and Vectors 10, 113.
  • Bensoussan, E., Nasereddin, A., Jonas, F., Schnur, L.F., Jaffe, C.L., 2006. Comparison of PCR assay for diagnosis of cutaneous leishmaniasis. Journal of Clinical Microbiology 44, 1435-1439.
  • Beyhan, Y.E., Çelebi, B., Ergene, O., Mungan, M., 2016. Hatay, Burdur ve Kuzey Kıbrıs Köpeklerinde Leishmaniasisin Seroprevalansı. Türkiye Parazitoloji Dergisi 40, 9-12.
  • Bourdeau, P., Saridomichelakis, M.N., Oliveria, A., Oliva, G., Kotnik, T., Galvez, R., Manzillo, V.F., Koutinas, A.F., Fonseca, I.F., Miró, G., 2014. Management of canine leishmaniosis in endemic SWEuropean regions: a questionnaire-based multinational survey. Parasites and Vectors 7, 110.
  • Cortes, S., Rolão, N., Ramada, J., Campino, L., 2004. PCR as a rapid and sensitive tool in the diagnosis of human and canine leishmaniasis using Leishmania donovani s.l.-specific kinetoplastid primers. Transactions of the Royal Society of Tropical Medicine and Hygiene 98, 12-17.
  • Cunze, S., Kochmann, J., Koch, L.K., Hasselmann, K.J.Q., Klimpel, S., 2019. Leishmaniasis in Eurasia and Africa: geographical distribution of vector species and pathogens. Royal Society Open Science 6, 190334.
  • Dantas-Torres, F., Solano-Gallego, L., Baneth, G., Ribeiro, V.M., de Paiva-Cavalcanti, M., Otranto, D., 2012. Canine leishmaniasis in the old and new world: Unveiled similarities and differences. Trends in Parasitology 28, 531-538.
  • Ertabaklar, H., Töz, S.Ö., Özkan, A.T., Rastgeldi, S., Balcıoglu, I.C., Özbel, Y., 2005. Serological and entomological survey in a zoonotic visceral leishmaniasis focus of North Central Anatolia, Turkey: Corum province. Acta Tropica 93, 239-246.
  • Galluzzi, L., Ceccarelli, M., Diotallevi, A., Menotta, M., Magnani, M., 2018. Real-time PCR applications for diagnosis of leishmaniasis. Parasites and Vectors 11, 1-13.
  • Gao, C.H., Ding, D., Wang, J.Y., Steverding, D., Wang, X., Yang, Y.T., Shi, F., 2015. Development of a LAMP assay for detection of Leishmania infantum infection in dogs using conjunctival swab samples. Parasites and Vectors 8, 370.
  • Hakkour, M., El Alem, M.M., Hmamouch, A., Rhalem, A., Delouane, B., Habbari, K., Fellah, H., Sadak, A., Sebti, F., 2019. Leishmaniasis in Northern Morocco: Predominance of Leishmania infantum Compared to Leishmania tropica. BioMed Research International 5327287.
  • Handman, E., 1999. Cell biology of Leishmania. Advances in Parasitology 44, 1-39.
  • İça, A., İnci, A., Yıldırım, A., Atalay, O., Düzlü, Ö., 2008. Kayseri ve Civarında Köpeklerde Leishmaniosisin Nested-PCR ile Araştırılması. Türkiye Parazitoloji Dergisi 32, 187-191.
  • Kaynaş, S., 2019. Burdur İli’nde Bulunan Kum Sineği (Diptera: Psychodidae) Populasyonları Ekolojisi Üzerine Araştırmalar. Yüksek Lisans Tezi, Burdur Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü, Burdur.
  • Koltaş, I.S., Eroğlu, F., Alabaz, D., Uzun, S., 2014. The emergence of Leishmania major and Leishmania donovani in southern Turkey. Transactions of the Royal Society of Tropical Medicine and Hygiene 108, 154-158.
  • Lachaud, L., Marchergui-Hammami, S., Chabbert, E., Dereure, J., Dedet, J.P., Bastien, P., 2002. Comparision of six PCR methods using peripheral blood for detection of canine visceral leishmaniasis. Journal of Clinical Microbiology 40, 210-215.
  • Lamotte, S., Spath, G.F., Rachidi, N., Prina, E., 2017. The enemy within: Targeting host-parasite interaction for antileishmanial drug discovery. PLoS Neglected Tropical Diseases 11, 1-14.
  • le Fichoux, Y., Quaranta, J.F., Aufeuvre, J.P., Lelievre, A., Marty, P., Suffia, I., Rousseau, D., Kubar, J., 1999. Occurrence of Leishmania infantum parasitemia in asymptomatic blood donors living in an area of endemicity in southern France. Journal of Clinical Microbiology 37, 1953-1957.
  • Marcondes, M., Day, M.J., 2019. Current status and management of canine leishmaniasis in Latin America. Research in Veterinary Science 123, 261-272.
  • Noyes, H.A., Reyburn, H., Bailey, J.W., Smith, D., 1998. A nested PCR based schizodeme method for identifying Leishmania kinetoplast minicircle classes directly from clinical samples and its application to the study of the epidemiology of Leishmania tropica in Pakistan. Journal of Clinical Microbiology 36, 2877-2881.
  • Olias-Molero, A.I., Corral, M.J., Jimenez-Anton, M.D., Alunda, J.M., 2019. Early antibody response and clinical outcome in experimental canine leishmaniasis. Nature, 9, 18606.
  • Özbel, Y., Oskam, L., Özensoy, S., Turgay, N., Alkan, M.Z., Jaffe, C.L., Özcel, M.A., 2000. A survey on canine leishmaniasis in western Turkey by parasite, DNA and antibody detection assays. Acta Tropica 74, 1-6.
  • Özensoy Töz, S., Sakru, N., Ertabaklar, H., Demir, S., Şengül, M., Özbel, Y., 2009. Serological and entomological survey of zoonotic visceral leishmaniasis in Denizli Province, Aegean Region, Turkey. New Microbiologica 32, 93-100.
  • Özerdem, D., Eroğlu, F., Genç, A., Demirkazık, M., Koltaş, I.S., 2009. Comparison of microscopic examination, rK39, and PCR for visceral leishmaniasis diagnosis in Turkey. Parasitology Research 106, 197-200.
  • Parker, L.A., Acosta, L., Gutierrez, M.N., Cruz, I., Nieto, J., Deschutter, E.J., Bornay-Llinares, F.J., 2021. A Novel Sampling Model to Study the Epidemiology of Canine Leishmaniasis in an Urban Environment. Frontiers in Veterinary Science 8, 642287.
  • Ready, P.D., 2014. Epidemiology of visceral leishmaniasis. Clinical Epidemiology 6, 147-154. Ribeiro, R.R., Michalick MSM da Silva, M.E., Cristiano dos Santos, C.P., Frézard FJG da Silva, S.M., 2018. Canine Leishmaniasis: An Overview of the Current Status and Strategies for Control. Hindawi BioMed Research International 6, 1-12.
  • Schallig, H.D., Oskam, L., 2002. Molecular biological applications in the diagnosis and control of leishmaniasis and parasite identification. Tropical Medicine and International Health 7, 641-651.
  • Slappendel, R.J., Greene, C.E., 1990. Leishmaniasis. In: Greene, C.E. (Ed.), Infectious diseases of the dog and cat. Philadelphia, Saunders Company, pp. 769-777.
  • Solano-Gallego, L., Koutinas, A., Miro, G., Cardoso, L., Pennisi. M.G., Ferrer, L., Bourdeau, P., Oliva, G., Baneth, G., 2009. Directions for the diagnosis, clinical staging, treatment and prevention of canine leishmaniosis. Veterinary Parasitology 165, 1-18.
  • Steverding, D., 2017. The history of leishmaniasis. Parasites and Vectors 10, 82.
  • Teimouri, A., Mohebali, M., Kazemirad, E., Hajjaran, H., 2018. Molecular Identification of Agents of Human Cutaneous Leishmaniasis and Canine Visceral Leishmaniasis in Different Areas of Iran Using Internal Transcribed Spacer 1 PCR-RFLP. Journal of Arthropod-Borne Diseases 12, 162-171.
  • Töz, S.Ö., Çulha, G., Zeyrek, F.Y., Ertabaklar, H., Alkan, M.Z., Vardarlı, A.T., Gündüz, C., Özbel, Y., 2013. A real-time ITS1-PCR based method in the diagnosis and species identification of leishmania parasite from human and dog clinical samples in Turkey. PLoS Neglected Tropical Diseases 7, 1-8.
  • Travi, B.L., Cordeiro-da-Silva, A., Dantas-Torres, F., MiroÂ, G., 2018. Canine visceral leishmaniasis: Diagnosis and management of the reservoir living among us. Neglected Tropical Diseases 12, 1-13.
  • Ünlü, A.H,, Düz, E., Bilgiç, H.B., Köse, O., Bakırcı, S., 2019. Van ve Bitlis İllerindeki Köpeklerde Leishmaniasis Seroprevalansı. Dicle Üniversitesi Veteriner Fakültesi Dergisi 12, 112-116.
  • Zeyrek, F.Y., Gürses, G., Uluca, N., Doni, N.Y., Toprak, Ş., Yeşilova, Y., Çulha, G., 2014. Is the agent of cutaneous leishmaniasis in Sanliurfa changing? First cases of Leishmania major. Türkiye Parazitoloji Dergisi 38, 270-274.

Molecular prevalence of canine leishmaniasis in Burdur, Türkiye

Year 2023, Volume: 11 Issue: 2, 244 - 252, 31.08.2023

Önder Özen Onur Köse

https://doi.org/10.24998/maeusabed.1340953

Abstract

Canine leishmaniasis (CanL) is among the most important vector-borne parasitic diseases in dogs worldwide, except for Oceania, and can be fatal if left untreated. The present study aimed to investigate the molecular prevalence of L. infantum, the causative agent of CanL, in Burdur province of Türkiye. Blood samples collected from 120 dogs were first examined for Leishmania spp. by genus-spesific PCR and then positives were examined for L. infantum/donovani complex by species-spesific PCR. As a result, Leishmania DNA was detected in five out of the 120 samples in the first-stage PCR, resulting in a molecular positivity rate of 4.16% at the genus level. Among these five samples, four were positive for L. infantum in the second-stage PCR, leading to a prevalence of 3.33% for L. infantum. No statistically significant differences were found in terms of gender and age concerning L. infantum positivity. Additionally, blood smears were examined under a microscope, but no Leishmania amastigotes were observed in any of the samples. With this obtained data, the presence of Leishmania spp. and L. infantum in dogs in Burdur is reported for the first time using a molecular method. The importance of vector fly control has been remembered once again in order to protect from the disease both animals that can be host of parasites, especially dogs, and human society, since it is a zoonotic disease.

Keywords

Burdur canine leishmaniasis Leishmania infantum PCR prevalence

Project Number

0753-YL-21

References

  • Akhoundi, M., Kuhls, K., Cannet, A., Votýpka, J., Marty, P., Delaunay, P., Sereno, D., 2016. A historical overview of the classification, evolution, and dispersion of Leishmania parasites and sandflies. PLoS Neglected Tropical Diseases 10, 1-40.
  • Akman, L., Aksu, H.S., Wang, R.Q., Özensoy, S., Özbel, Y., Alkan, Z., Özcel, M.A., Çulha, G., Özcan, K., Uzun, S., Memişoglu, H.R., Chang, K.P., 2000. Multi-site DNA polymorphism analyses of Leishmania isolates define their genotypes predicting clinical epidemiology of leishmaniasis in a specific region. Journal of Eukaryotic Microbiology 47, 545-554.
  • Alemayehu, B., Alemayehu, M., 2017. Leishmaniasis: A Review on Parasite, Vector and Reservoir Host. Health Science Journal 11, 519.
  • Andrade, H.M., Reis, A.B., Santos, S.L., Volpini, A.C., Marques, M.J., Romanha, A.J., 2006. Use of PCR-RFLP to identify Leishmania species in naturally-infected dogs. Veterinary Parasitology 140, 231-238.
  • Aslan Çelik, B., Şahin, T., Çelik, Ö., 2019. Retrospective Evaluation of Canine Leishmaniasis in Turkey. Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi 33, 123-130.
  • Aydenizöz, M., Yağcı, B.B., Taylan Özkan, A., Duru, S.Y., Gazyağcı, A.N., 2010. Investigation of the prevalence of visceral leishmaniasis by the microculture method and IFAT in dogs in Kırıkkale. Türkiye Parazitoloji Dergisi 34, 1-5.
  • Ayele, A., Seyoum, Z., 2016. A Review on Canine Leishmaniasis; Etiology, Clinical Sign, Pathogenesis, Treatment and Control Methods. Global Veterinaria 17, 343-352.
  • Bakırcı, S., Bilgiç, H.B., Köse, O., Aksulu, A., Hacılarlıoğlu, S., Erdoğan, H., Karagenç, T., 2016. Molecular and seroprevalence of canine visceral leishmaniasis in West Anatolia, Turkey. Turkish Journal of Veterinary and Animal Sciences 40, 637-644.
  • Bakırcı, S., Topçuoğlu, A.D., 2021. Molecular and Serological Analysis for Prevalence of Canine Visceral Leishmaniasis in the Muğla Region of Turkey. Türkiye Parazitoloji Dergisi 45, 11-16.
  • Bamorovat, M., Sharifi, I., Dabiri, S., Mohammadi, M.A., Harandi, M.F., Mohebali, M., Aflatoonian, M.R., Keyhani, A., 2015. Leishmania tropica in Stray Dogs in Southeast Iran. Iranian Journal of Public Health 44, 1359-1366.
  • Baneth, G., Koutinas, A.F., Solano-Gallego, L., Bourdeau, P., Ferrer, L., 2008. Canine leishmaniosis – new concepts and insights on an expanding zoonosis: part one. Trends in Parasitology 24, 324-330.
  • Baneth, G., Zivotofsky, D., Nachum-Biala, Y., Yasur-Landau, D., Botero, A.M., 2014. Mucocutaneous Leishmania tropica infection in a dog from a human cutaneous leishmaniasis focus. Parasites and Vectors 7, 1-5.
  • Baneth, G., Yasur-Landau, D., Gilad, M., Nachum-Biala, Y., 2017. Canine leishmaniosis caused by Leishmania major and Leishmania tropica: comparative findings and serology. Parasites and Vectors 10, 113.
  • Bensoussan, E., Nasereddin, A., Jonas, F., Schnur, L.F., Jaffe, C.L., 2006. Comparison of PCR assay for diagnosis of cutaneous leishmaniasis. Journal of Clinical Microbiology 44, 1435-1439.
  • Beyhan, Y.E., Çelebi, B., Ergene, O., Mungan, M., 2016. Hatay, Burdur ve Kuzey Kıbrıs Köpeklerinde Leishmaniasisin Seroprevalansı. Türkiye Parazitoloji Dergisi 40, 9-12.
  • Bourdeau, P., Saridomichelakis, M.N., Oliveria, A., Oliva, G., Kotnik, T., Galvez, R., Manzillo, V.F., Koutinas, A.F., Fonseca, I.F., Miró, G., 2014. Management of canine leishmaniosis in endemic SWEuropean regions: a questionnaire-based multinational survey. Parasites and Vectors 7, 110.
  • Cortes, S., Rolão, N., Ramada, J., Campino, L., 2004. PCR as a rapid and sensitive tool in the diagnosis of human and canine leishmaniasis using Leishmania donovani s.l.-specific kinetoplastid primers. Transactions of the Royal Society of Tropical Medicine and Hygiene 98, 12-17.
  • Cunze, S., Kochmann, J., Koch, L.K., Hasselmann, K.J.Q., Klimpel, S., 2019. Leishmaniasis in Eurasia and Africa: geographical distribution of vector species and pathogens. Royal Society Open Science 6, 190334.
  • Dantas-Torres, F., Solano-Gallego, L., Baneth, G., Ribeiro, V.M., de Paiva-Cavalcanti, M., Otranto, D., 2012. Canine leishmaniasis in the old and new world: Unveiled similarities and differences. Trends in Parasitology 28, 531-538.
  • Ertabaklar, H., Töz, S.Ö., Özkan, A.T., Rastgeldi, S., Balcıoglu, I.C., Özbel, Y., 2005. Serological and entomological survey in a zoonotic visceral leishmaniasis focus of North Central Anatolia, Turkey: Corum province. Acta Tropica 93, 239-246.
  • Galluzzi, L., Ceccarelli, M., Diotallevi, A., Menotta, M., Magnani, M., 2018. Real-time PCR applications for diagnosis of leishmaniasis. Parasites and Vectors 11, 1-13.
  • Gao, C.H., Ding, D., Wang, J.Y., Steverding, D., Wang, X., Yang, Y.T., Shi, F., 2015. Development of a LAMP assay for detection of Leishmania infantum infection in dogs using conjunctival swab samples. Parasites and Vectors 8, 370.
  • Hakkour, M., El Alem, M.M., Hmamouch, A., Rhalem, A., Delouane, B., Habbari, K., Fellah, H., Sadak, A., Sebti, F., 2019. Leishmaniasis in Northern Morocco: Predominance of Leishmania infantum Compared to Leishmania tropica. BioMed Research International 5327287.
  • Handman, E., 1999. Cell biology of Leishmania. Advances in Parasitology 44, 1-39.
  • İça, A., İnci, A., Yıldırım, A., Atalay, O., Düzlü, Ö., 2008. Kayseri ve Civarında Köpeklerde Leishmaniosisin Nested-PCR ile Araştırılması. Türkiye Parazitoloji Dergisi 32, 187-191.
  • Kaynaş, S., 2019. Burdur İli’nde Bulunan Kum Sineği (Diptera: Psychodidae) Populasyonları Ekolojisi Üzerine Araştırmalar. Yüksek Lisans Tezi, Burdur Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü, Burdur.
  • Koltaş, I.S., Eroğlu, F., Alabaz, D., Uzun, S., 2014. The emergence of Leishmania major and Leishmania donovani in southern Turkey. Transactions of the Royal Society of Tropical Medicine and Hygiene 108, 154-158.
  • Lachaud, L., Marchergui-Hammami, S., Chabbert, E., Dereure, J., Dedet, J.P., Bastien, P., 2002. Comparision of six PCR methods using peripheral blood for detection of canine visceral leishmaniasis. Journal of Clinical Microbiology 40, 210-215.
  • Lamotte, S., Spath, G.F., Rachidi, N., Prina, E., 2017. The enemy within: Targeting host-parasite interaction for antileishmanial drug discovery. PLoS Neglected Tropical Diseases 11, 1-14.
  • le Fichoux, Y., Quaranta, J.F., Aufeuvre, J.P., Lelievre, A., Marty, P., Suffia, I., Rousseau, D., Kubar, J., 1999. Occurrence of Leishmania infantum parasitemia in asymptomatic blood donors living in an area of endemicity in southern France. Journal of Clinical Microbiology 37, 1953-1957.
  • Marcondes, M., Day, M.J., 2019. Current status and management of canine leishmaniasis in Latin America. Research in Veterinary Science 123, 261-272.
  • Noyes, H.A., Reyburn, H., Bailey, J.W., Smith, D., 1998. A nested PCR based schizodeme method for identifying Leishmania kinetoplast minicircle classes directly from clinical samples and its application to the study of the epidemiology of Leishmania tropica in Pakistan. Journal of Clinical Microbiology 36, 2877-2881.
  • Olias-Molero, A.I., Corral, M.J., Jimenez-Anton, M.D., Alunda, J.M., 2019. Early antibody response and clinical outcome in experimental canine leishmaniasis. Nature, 9, 18606.
  • Özbel, Y., Oskam, L., Özensoy, S., Turgay, N., Alkan, M.Z., Jaffe, C.L., Özcel, M.A., 2000. A survey on canine leishmaniasis in western Turkey by parasite, DNA and antibody detection assays. Acta Tropica 74, 1-6.
  • Özensoy Töz, S., Sakru, N., Ertabaklar, H., Demir, S., Şengül, M., Özbel, Y., 2009. Serological and entomological survey of zoonotic visceral leishmaniasis in Denizli Province, Aegean Region, Turkey. New Microbiologica 32, 93-100.
  • Özerdem, D., Eroğlu, F., Genç, A., Demirkazık, M., Koltaş, I.S., 2009. Comparison of microscopic examination, rK39, and PCR for visceral leishmaniasis diagnosis in Turkey. Parasitology Research 106, 197-200.
  • Parker, L.A., Acosta, L., Gutierrez, M.N., Cruz, I., Nieto, J., Deschutter, E.J., Bornay-Llinares, F.J., 2021. A Novel Sampling Model to Study the Epidemiology of Canine Leishmaniasis in an Urban Environment. Frontiers in Veterinary Science 8, 642287.
  • Ready, P.D., 2014. Epidemiology of visceral leishmaniasis. Clinical Epidemiology 6, 147-154. Ribeiro, R.R., Michalick MSM da Silva, M.E., Cristiano dos Santos, C.P., Frézard FJG da Silva, S.M., 2018. Canine Leishmaniasis: An Overview of the Current Status and Strategies for Control. Hindawi BioMed Research International 6, 1-12.
  • Schallig, H.D., Oskam, L., 2002. Molecular biological applications in the diagnosis and control of leishmaniasis and parasite identification. Tropical Medicine and International Health 7, 641-651.
  • Slappendel, R.J., Greene, C.E., 1990. Leishmaniasis. In: Greene, C.E. (Ed.), Infectious diseases of the dog and cat. Philadelphia, Saunders Company, pp. 769-777.
  • Solano-Gallego, L., Koutinas, A., Miro, G., Cardoso, L., Pennisi. M.G., Ferrer, L., Bourdeau, P., Oliva, G., Baneth, G., 2009. Directions for the diagnosis, clinical staging, treatment and prevention of canine leishmaniosis. Veterinary Parasitology 165, 1-18.
  • Steverding, D., 2017. The history of leishmaniasis. Parasites and Vectors 10, 82.
  • Teimouri, A., Mohebali, M., Kazemirad, E., Hajjaran, H., 2018. Molecular Identification of Agents of Human Cutaneous Leishmaniasis and Canine Visceral Leishmaniasis in Different Areas of Iran Using Internal Transcribed Spacer 1 PCR-RFLP. Journal of Arthropod-Borne Diseases 12, 162-171.
  • Töz, S.Ö., Çulha, G., Zeyrek, F.Y., Ertabaklar, H., Alkan, M.Z., Vardarlı, A.T., Gündüz, C., Özbel, Y., 2013. A real-time ITS1-PCR based method in the diagnosis and species identification of leishmania parasite from human and dog clinical samples in Turkey. PLoS Neglected Tropical Diseases 7, 1-8.
  • Travi, B.L., Cordeiro-da-Silva, A., Dantas-Torres, F., MiroÂ, G., 2018. Canine visceral leishmaniasis: Diagnosis and management of the reservoir living among us. Neglected Tropical Diseases 12, 1-13.
  • Ünlü, A.H,, Düz, E., Bilgiç, H.B., Köse, O., Bakırcı, S., 2019. Van ve Bitlis İllerindeki Köpeklerde Leishmaniasis Seroprevalansı. Dicle Üniversitesi Veteriner Fakültesi Dergisi 12, 112-116.
  • Zeyrek, F.Y., Gürses, G., Uluca, N., Doni, N.Y., Toprak, Ş., Yeşilova, Y., Çulha, G., 2014. Is the agent of cutaneous leishmaniasis in Sanliurfa changing? First cases of Leishmania major. Türkiye Parazitoloji Dergisi 38, 270-274.
There are 47 citations in total.

Details

Primary Language English
Subjects Veterinary Parasitology
Journal Section Research Article
Authors

Önder Özen This is me 0000-0003-0653-5519

Onur Köse 0000-0002-4021-7429

Project Number 0753-YL-21
Publication Date August 31, 2023
Submission Date August 10, 2023
Published in Issue Year 2023 Volume: 11 Issue: 2

Cite

APA Özen, Ö., & Köse, O. (2023). Molecular prevalence of canine leishmaniasis in Burdur, Türkiye. Mehmet Akif Ersoy University Journal of Health Sciences Institute, 11(2), 244-252. https://doi.org/10.24998/maeusabed.1340953
AMA Özen Ö, Köse O. Molecular prevalence of canine leishmaniasis in Burdur, Türkiye. Mehmet Akif Ersoy University Journal of Health Sciences Institute. August 2023;11(2):244-252. doi:10.24998/maeusabed.1340953
Chicago Özen, Önder, and Onur Köse. “Molecular Prevalence of Canine Leishmaniasis in Burdur, Türkiye”. Mehmet Akif Ersoy University Journal of Health Sciences Institute 11, no. 2 (August 2023): 244-52. https://doi.org/10.24998/maeusabed.1340953.
EndNote Özen Ö, Köse O (August 1, 2023) Molecular prevalence of canine leishmaniasis in Burdur, Türkiye. Mehmet Akif Ersoy University Journal of Health Sciences Institute 11 2 244–252.
IEEE Ö. Özen and O. Köse, “Molecular prevalence of canine leishmaniasis in Burdur, Türkiye”, Mehmet Akif Ersoy University Journal of Health Sciences Institute, vol. 11, no. 2, pp. 244–252, 2023, doi: 10.24998/maeusabed.1340953.
ISNAD Özen, Önder - Köse, Onur. “Molecular Prevalence of Canine Leishmaniasis in Burdur, Türkiye”. Mehmet Akif Ersoy University Journal of Health Sciences Institute 11/2 (August 2023), 244-252. https://doi.org/10.24998/maeusabed.1340953.
JAMA Özen Ö, Köse O. Molecular prevalence of canine leishmaniasis in Burdur, Türkiye. Mehmet Akif Ersoy University Journal of Health Sciences Institute. 2023;11:244–252.
MLA Özen, Önder and Onur Köse. “Molecular Prevalence of Canine Leishmaniasis in Burdur, Türkiye”. Mehmet Akif Ersoy University Journal of Health Sciences Institute, vol. 11, no. 2, 2023, pp. 244-52, doi:10.24998/maeusabed.1340953.
Vancouver Özen Ö, Köse O. Molecular prevalence of canine leishmaniasis in Burdur, Türkiye. Mehmet Akif Ersoy University Journal of Health Sciences Institute. 2023;11(2):244-52.
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