Abstract
References
- 1. Lesher G. Y., Froelich E. J., Gruett M. D., Bailey J.H., Brundage R. P., 1962. 1,8-Naphthyridine Derivatives. A New Class of Chemotherapeutic Agents. J Med Pharm Chem, 5(5), 1063–1065. 2. Badawy S., Yang Y., Liu Y., Marawan M. A., Ares I., Martinez M. A., Martínez M., Wang Xu., Anadon A., Martínez M., 2021. Toxicity induced by ciprofloxacin and enrofloxacin: oxidative stress and metabolism. Critical Reviews in Toxicology, 51(9), 754-787.
- 3. Hampshire V. A., Doddy F. M., Post L. O., Koogler T. L., Burgess T. M., Batten P. O., Hudson R., McAdams D. R., Brown M.A., 2004. Adverse drug event reports at the United States food and drug Administration Center for Veterinary Medicine. Journal-Amerıcan Veterınary Medıcal Assocıatıon, 225(4), 533-537.
- 4. Giuliano E, A., Van Der Woerdt A., 1999. Feline retinal degeneration: clinical experience and new findings (1994-1997). Journal of the American Animal Hospital Association, 35(6), 511-514.
- 5. Gelatt K. N., Van Der Woerdt A., Ketring K. L., Andrew S. E., Brooks D. E., Biros D. J., Denis M. H., Cutler T. J., 2001. Enrofloxacin-associated retinal degeneration in cats. Veterinary Ophthalmology, 4(2), 99-106.
- 6. Ford M. M., Dubielzig R. R., Giuliano E.A., Moore C. P., Narfström K. L., 2007. Ocular and systemic manifestations after oral administration of a high dose of enrofloxacin in cats. Am J Vet Res, 68(2), 190-202.
- 7. Clinical Hematology - Clinical Pathology and Procedures - MSD Veterinary Manual [Internet]. [cited 2022 Dec 21]. Available from: https://www.msdvetmanual.com/clinical- pathology-and-procedures/diagnostic- procedures-for-the-private-practice- laboratory/clinical-hematology
Abstract
This case report, it was aimed to give information about enrofloxacin toxicity in a cat. The case material consisted of an 8-month-old tabby female cat, weighing 1.4 kilograms, brought to the emergency department with complaints of vomiting, diarrhea, weakness, tremor, dyspnea and inability to walk. According to the anamnesis, it was stated that the appetite of the animal was not good and that he received antibiotic treatment. It was stated that after the treatment, the inability to walk and the incoordination took shape. It was determined by us while taking the anamnesis information that the patient's owners were continuing the antibiotic treatment. Likewise, it was learned that 0.7 ml (35 mg) of the preparation containing the active ingredient of enrofloxacin was administered. This dose was found to correspond to 5 times the normal dose of “0.14 ml (7 mg)”. An ophthalmological examination was not performed. However, it was observed that he did not respond to the pupillary reflex. The case was evaluated as enrofloxacin toxicity. As a result, it was evaluated that high-dose enrofloxacin may result in vision loss, as in this case.
Keywords
References
- 1. Lesher G. Y., Froelich E. J., Gruett M. D., Bailey J.H., Brundage R. P., 1962. 1,8-Naphthyridine Derivatives. A New Class of Chemotherapeutic Agents. J Med Pharm Chem, 5(5), 1063–1065. 2. Badawy S., Yang Y., Liu Y., Marawan M. A., Ares I., Martinez M. A., Martínez M., Wang Xu., Anadon A., Martínez M., 2021. Toxicity induced by ciprofloxacin and enrofloxacin: oxidative stress and metabolism. Critical Reviews in Toxicology, 51(9), 754-787.
- 3. Hampshire V. A., Doddy F. M., Post L. O., Koogler T. L., Burgess T. M., Batten P. O., Hudson R., McAdams D. R., Brown M.A., 2004. Adverse drug event reports at the United States food and drug Administration Center for Veterinary Medicine. Journal-Amerıcan Veterınary Medıcal Assocıatıon, 225(4), 533-537.
- 4. Giuliano E, A., Van Der Woerdt A., 1999. Feline retinal degeneration: clinical experience and new findings (1994-1997). Journal of the American Animal Hospital Association, 35(6), 511-514.
- 5. Gelatt K. N., Van Der Woerdt A., Ketring K. L., Andrew S. E., Brooks D. E., Biros D. J., Denis M. H., Cutler T. J., 2001. Enrofloxacin-associated retinal degeneration in cats. Veterinary Ophthalmology, 4(2), 99-106.
- 6. Ford M. M., Dubielzig R. R., Giuliano E.A., Moore C. P., Narfström K. L., 2007. Ocular and systemic manifestations after oral administration of a high dose of enrofloxacin in cats. Am J Vet Res, 68(2), 190-202.
- 7. Clinical Hematology - Clinical Pathology and Procedures - MSD Veterinary Manual [Internet]. [cited 2022 Dec 21]. Available from: https://www.msdvetmanual.com/clinical- pathology-and-procedures/diagnostic- procedures-for-the-private-practice- laboratory/clinical-hematology
Details
| Primary Language | English |
|---|---|
| Subjects | Veterinary Internal Medicine |
| Journal Section | Case Reports |
| Authors | |
| Publication Date | December 30, 2022 |
| Published in Issue | Year 2022 Volume: 2 Issue: 1-2 |
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